Chemicals with Transgenerational Effects on Disease or Function

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No. Chemical Name GO Biological Process Effect Specific BP GO Species Description PMID
1336Melphalanmale gamete generationdecreasespermatogenesisGO:0007283Mus musculusMelphalan, alone or conjugated to an FSH-24746827
1337Melphalanmale gamete generationaffectmale germ-line mutationsN/AMus musculusMelphalan, a second chemical for which specific-locus mutation induction in the mouse is maximum in early spermatids.1378547, 8552138
1338Methioninemale gamete generationaffectspermatogenesisGO:0007283Mus musculus[Choline deficiency co-treated with Methionine deficiency] affects spermatogenesis33940107
1339Methyl Parathionmale gamete generationdecreasespermatid developmentGO:0007286Mus musculusalpha-Tocopherol inhibits the reaction [Methyl Parathion results in decreased spermatid development]32294493
1340Methyl Parathionmale gamete generationdecreasespermatid developmentGO:0007286Mus musculusMethyl Parathion results in decreased spermatid development32294493
1341Miglustatmale gamete generationaffectspermatogenesisGO:0007283Mus musculusMiglustat affects spermatogenesis.17067996
1342Mitoquinonemale gamete generationdecreasespermatogenesisGO:0007283Mus musculusMitoquinone inhibits the reaction [triptolide results in decreased spermatogenesis]30836114
1343Mono(2-ethyl-5-hydroxyhexyl) phthalatemale gamete generationdecreasespermatogenesisGO:0007283Homo sapiens[Diethylhexyl Phthalate results in increased abundance of mono(2-ethyl-5-hydroxyhexyl) phthalate] which results in decreased spermatogenesis18570050
1344Mono(2-ethyl-5-oxohexyl)phthalatemale gamete generationdecreasespermatogenesisGO:0007283Homo sapiens[Diethylhexyl Phthalate results in increased abundance of mono(2-ethyl-5-oxohexyl)phthalate] which results in decreased spermatogenesis18570050
1345Mono(2-ethylhexyl) phthalate (MEHP)male gamete generationaffectspermatogenesisGO:0007283Mus musculusGenistein and mono(2-ethylhexyl) phthalate (MEHP)? disrupt the eicosanoid pathway in Spermatogonial Stem Cells.34942354
1346Mono(2-ethylhexyl) phthalate (MEHP)male gamete generationaffectspermatogenesisGO:0007283Mus musculusGenistein and mono(2-ethylhexyl) phthalate (MEHP) increase Spermatogonial Stem Cell differentiation markers.34942354
1347Mono(2-ethylhexyl) phthalate (MEHP)male gamete generationaffectspermatogenesisGO:0007283Mus musculusGenistein and mono(2-ethylhexyl) phthalate (MEHP) may affect Spermatogonial Stem Cell differentiation by altering eicosanoids.34942354
1348Monobutyl phthalatemale gamete generationdecreasespermatogenesisGO:0007283Mus musculusmonobutyl phthalate results in decreased spermatogenesis28496037
1349Monobutyl phthalatemale gamete generationdecreasespermatogenesisGO:0007283Homo sapiens[Dibutyl Phthalate results in increased abundance of monobutyl phthalate] which results in decreased spermatogenesis17003688
1350Monobutyl phthalatemale gamete generationdecreasespermatogenesisGO:0007283Homo sapiens[diethyl phthalate results in increased abundance of monoethyl phthalate] which results in decreased spermatogenesis18570050

Showing 1336 to 1350 of 1481 entries

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Copyright © Haifeng Chen Lab, Shanghai Jiao Tong University.