positive regulation of flagellated sperm motility involved in capacitation
GO:0060474
Homo sapiens
4-((2-(oTolyloxy)quinolin-3-yl)methyl)-2-phenyl-2H-
1,2,4-triazol-3(4H)-one (2OQT) exhibited no significant enhancement in sperm progressive motility and survival.
positive regulation of flagellated sperm motility involved in capacitation
GO:0060474
Homo sapiens
4-((2-(pTolyloxy)quinolin-3-yl)methyl)-2-phenyl-2H-
1,2,4-triazol-3(4H)-one (2PQT) exhibited no significant enhancement in sperm progressive motility and survival.
positive regulation of flagellated sperm motility involved in capacitation
GO:0060474
Homo sapiens
4-((2,6-Dichloroquinolin-3-yl)methyl)-2-phenyl-2H-
1,2,4-triazol-3(4H)-one (2,6CQT) exhibited no significant enhancement in sperm progressive motility and survival.
positive regulation of flagellated sperm motility involved in capacitation
GO:0060474
Homo sapiens
4-((2-Chloro-6-methoxyquinolin-3-yl)methyl)-2-phenyl-2H-1,2,4-triazol-3(4H)-one (2,6MQT) exhibited no significant enhancement in sperm progressive motility and survival.
positive regulation of flagellated sperm motility involved in capacitation
GO:0060474
Homo sapiens
4-((2-Chloroquinolin-3yl)methyl)-2-phenyl-2H-
1,2,4-triazol-3(4H)-one (2CQT) exhibited no significant enhancement in sperm progressive motility and survival.
positive regulation of flagellated sperm motility involved in capacitation
GO:0060474
Homo sapiens
4-((2-Hydroxy-6-methoxyquinolin-3-yl)methyl)-2-phenyl-2H-1,2,4-triazol-3(4H)-one (2,6HQT) exhibited no significant enhancement in sperm progressive motility and survival.
positive regulation of flagellated sperm motility involved in capacitation
GO:0060474
Homo sapiens
4-((2-Hydroxyquinolin-3-yl)methyl)-2-phenyl-2H-1,2,4-triazol-3(4H)-one (2HQT) exhibited no significant enhancement in sperm progressive motility and survival.
33237520
1103
4-hydroxybenzophenone
male gamete generation
decrease
spermatogenesis
GO:0007283
Homo sapiens
4-hydroxybenzophenone results in decreased spermatogenesis
30245359
1104
4-nonylphenol
male gamete generation
decrease
spermatogenesis
GO:0007283
Mus musculus
[Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in decreased spermatogenesis
29029336
1105
4-tert-octylphenol
male gamete generation
decrease
spermatogenesis
GO:0007283
Mus musculus
4-tert-octylphenol results in decreased spermatogenesis
29029336
1106
4-tert-octylphenol
male gamete generation
decrease
spermatogenesis
GO:0007283
Mus musculus
[Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in decreased spermatogenesis
29029336
1107
6MQT
male gamete generation
increase
positive regulation of flagellated sperm motility involved in capacitation
GO:0060474
Mus musculus
Quinoline derivative 6MQT has significant sperm motility enhancement property under in vitro conditions. (6MQT ((4-((2-Chloro-6-methoxyquinolin-3-yl)methyl)-2-(4-methoxyphenyl)-2H-1,2,4-triazol-3(4H)-one))
33237520
1108
6MQT
male gamete generation
increase
positive regulation of flagellated sperm motility involved in capacitation
GO:0060474
Homo sapiens
2 compounds (6MQT and 2,6DQT) exhibited significant beneficial effect on sperm motility enhancement. Both the compounds improved the sperm motility, and enhanced kinetic parameters. (6MQT ((4-((2-Chloro-6-methoxyquinolin-3-yl)methyl)-2-(4-methoxyphenyl)-2H-1,2,4-triazol-3(4H)-one, 2,6DQT ((4-((2,6-Dichloroquinolin-3-yl)methyl)-2-(4-methoxyphenyl)-2H-1,2,4-triazol-3(4H)-one))
33237520
1109
Acephate?
male gamete generation
affect
sperm DNA aberrations
N/A
Homo sapiens
Extensive use of organophosphorus pesticides (OPs) could alter semen quality and sperm DNA at different stages of spermatogenesis.
28392800
1110
Acetamiprid
male gamete generation
affect
spermatogenesis
GO:0007283
Mus musculus
acetamiprid affects spermatogenesis
30103633
For any questions on the database, please send E-mail to caoyuedi@sjtu.edu.cn.
