Chemicals with Transgenerational Effects on Disease or Function
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entries
No.
Chemical Name
GO Biological Process
Effect
Specific BP
GO
Species
Description
PMID
1021
Dimethylformamide
fertilization
decrease
female pronucleus assembly
GO:0035038
Mus musculus
Dimethylformamide results in decreased female pronucleus assembly
35238128
1022
Dimethylformamide
fertilization
decrease
male pronucleus assembly
GO:0035039
Mus musculus
Dimethylformamide results in decreased male pronucleus assembly
35238128
1023
Dimethylformamide
fertilization
increase
negative regulation of fertilization
GO:0060467
Mus musculus
Dimethylformamide results in increased negative regulation of fertilization
35238128
1024
Enkephalin, D-Penicillamine (2,5)-
fertilization
decrease
fertilization
GO:0009566
Mus musculus
Enkephalin, D-Penicillamine (2,5)- results in decreased fertilization
32145291
1025
Enkephalin, D-Penicillamine (2,5)-
fertilization
decrease
fertilization
GO:0009566
Mus musculus
[Enkephalin, D-Penicillamine (2,5)- results in decreased sperm capacitation] which results in decreased fertilization
32145291
1026
Enkephalin, D-Penicillamine (2,5)-
fertilization
decrease
fertilization
GO:0009566
Mus musculus
[[Enkephalin, D-Penicillamine (2,5)- results in decreased sperm capacitation] which results in decreased fertilization] which results in decreased cytogamy
32145291
1027
Ethinyl Estradiol
fertilization
decrease
binding of sperm to zona pellucida
GO:0007339
Mus musculus
Ethinyl Estradiol results in decreased binding of sperm to zona pellucida
31931096
1028
Ethinyl Estradiol
fertilization
decrease
binding of sperm to zona pellucida
GO:0007339
Mus musculus
Melatonin inhibits the reaction [Ethinyl Estradiol results in decreased binding of sperm to zona pellucida]
31931096
1029
Ethinyl Estradiol
fertilization
decrease
binding of sperm to zona pellucida
GO:0007339
Mus musculus
[Ethinyl Estradiol results in increased cleavage of ZP2 protein] which results in decreased binding of sperm to zona pellucida
31931096
1030
Ethinyl Estradiol
fertilization
decrease
binding of sperm to zona pellucida
GO:0007339
Mus musculus
Melatonin inhibits the reaction [[Ethinyl Estradiol results in increased cleavage of ZP2 protein] which results in decreased binding of sperm to zona pellucida]
31931096
1031
Ethinyl Estradiol
fertilization
decrease
fertilization
GO:0009566
Mus musculus
Ethinyl Estradiol results in decreased fertilization
31931096
1032
Ethinyl Estradiol
fertilization
decrease
fertilization
GO:0009566
Mus musculus
Melatonin inhibits the reaction [Ethinyl Estradiol results in decreased fertilization]
31931096
1033
Fenoxaprop ethyl
fertilization
decrease
binding of sperm to zona pellucida
GO:0007339
Mus musculus
Melatonin inhibits the reaction [fenoxaprop ethyl results in decreased binding of sperm to zona pellucida]
31265864
1034
Fenoxaprop ethyl
fertilization
decrease
binding of sperm to zona pellucida
GO:0007339
Mus musculus
Fenoxaprop ethyl results in decreased binding of sperm to zona pellucida
31265864
1035
Fipronil
fertilization
decrease
fertilization
GO:0009566
Mus musculus
Fipronil results in decreased fertilization
32294523
For any questions on the database, please send E-mail to caoyuedi@sjtu.edu.cn.
