Chemicals with Transgenerational Effects on Disease or Function

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No. Chemical Name GO Biological Process Effect Specific BP GO Species Description PMID
676Bisphenol Ffemale gamete generationdecreaseoocyte maturationGO:0001556Mus musculusbisphenol F results in decreased oocyte maturation29102535
677Bisphenol Ffemale gamete generationdecreaseoocyte maturationGO:0001556Mus musculus[bisphenol F results in decreased oocyte maturation] which results in decreased polar body extrusion after meiotic divisions29102535
678BpV(pic)female gamete generationincreasefollicle developmentN/AHomo sapiensIn the bpV(pic)-treated group, 4-fold increases in the number of secondary and antral follicles were found. 20479243
679BpV(pic)female gamete generationincreaseoocyte maturationGO:0001556Homo sapiens4- and 27-fold increases in the number of antral follicles and mature (MI and MII) oocytes were found after bpV(pic) treatment.20479243
680Busulfanfemale gamete generationdecreasefollicle lossN/AMus musculusTreatment with busulfan for 30 days can accelerate the senescence of female mice, down-regulating the expression of estrogen in ovary, decreasing the number of all kinds of follicles.27806317, 23549849
681Butadiene diepoxidefemale gamete generationaffectoocyte chromosome aberrationsN/AMus musculusInduction and transmission of chromosome aberrations in mouse oocytes after treatment with butadiene diepoxide9435881
682Butylbenzyl phthalatefemale gamete generationincreaseoocyte developmentGO:0048599Mus musculus[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased oocyte development28013214
683Cadmiumfemale gamete generationincreasenegative regulation of meiotic cell cycle process involved in oocyte maturationGO:1904145Mus musculusCadmium results in increased negative regulation of meiotic cell cycle process involved in oocyte maturation29684212
684Cadmium Chloridefemale gamete generationdecreasemeiotic cell cycle process involved in oocyte maturationGO:1903537Mus musculusCadmium Chloride results in decreased meiotic cell cycle process involved in oocyte maturation29287790
685Capric acidfemale gamete generationNotoogenesisGO:0048477Mus musculusNot significantly changed metabolites during meiotic maturation (GV, GVBD, MII) (Metabolomics data: ultra-high-performance liquid chromatography-tandem high-resolution mass spectrometry (UHPLC-HRMS))33068521
686Carbenoxolonefemale gamete generationincreasepositive regulation of meiotic cell cycle process involved in oocyte maturationGO:1904146Mus musculusCarbenoxolone inhibits the reaction [EGF protein results in increased positive regulation of meiotic cell cycle process involved in oocyte maturation]29458137
687Carbenoxolonefemale gamete generationincreasepositive regulation of meiotic cell cycle process involved in oocyte maturationGO:1904146Mus musculusCarbenoxolone inhibits the reaction [[EGF protein results in increased positive regulation of meiotic cell cycle process involved in oocyte maturation] which results in increased meiotic metaphase II]29458137
688Carbenoxolonefemale gamete generationincreasepositive regulation of meiotic cell cycle process involved in oocyte maturationGO:1904146Mus musculus[Carbenoxolone inhibits the reaction [EGF protein results in increased positive regulation of meiotic cell cycle process involved in oocyte maturation]] which results in increased meiotic prophase I29458137
689Carbofuranfemale gamete generationdecreaseoocyte microtubule cytoskeleton organizationGO:0016325Mus musculusCarbofuran results in decreased oocyte microtubule cytoskeleton organization25564422
690CEP 33779female gamete generationdecreaseoocyte maturationGO:0001556Mus musculusCEP 33779 results in decreased oocyte maturation28615348

Showing 676 to 690 of 1481 entries

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Copyright © Haifeng Chen Lab, Shanghai Jiao Tong University.