Chemicals with Transgenerational Effects on Disease or Function
Show
entries
No.
Chemical Name
GO Biological Process
Effect
Specific BP
GO
Species
Description
PMID
631
5-Aminolevulinic acid
female gamete generation
Not
oogenesis
GO:0048477
Mus musculus
Not significantly changed metabolites during meiotic maturation (GV, GVBD, MII) (Metabolomics data: ultra-high-performance liquid chromatography-tandem high-resolution mass spectrometry (UHPLC-HRMS))
33068521
632
5-Hydroxylysine
female gamete generation
Not
oogenesis
GO:0048477
Mus musculus
Not significantly changed metabolites during meiotic maturation (GV, GVBD, MII) (Metabolomics data: ultra-high-performance liquid chromatography-tandem high-resolution mass spectrometry (UHPLC-HRMS))
33068521
633
5-Hydroxymethyl-2-Deoxyuridine
female gamete generation
Not
oogenesis
GO:0048477
Mus musculus
Not significantly changed metabolites during meiotic maturation (GV, GVBD, MII) (Metabolomics data: ultra-high-performance liquid chromatography-tandem high-resolution mass spectrometry (UHPLC-HRMS))
33068521
634
5'-Methylthioadenosine
female gamete generation
related
oogenesis
GO:0048477
Mus musculus
Significantly changed metabolites during meiotic maturation (GV, GVBD, MII) (Metabolomics data: ultra-high-performance liquid chromatography-tandem high-resolution mass spectrometry (UHPLC-HRMS))
33068521
635
5'-N-ethylcarboxamidoadenosine (NECA)
female gamete generation
not
meiotic cell cycle process involved in oocyte maturation
GO:1903537
Mus musculus
A dose-response experiment was conducted to assess
the action of six different adenosine analogs on hypoxanthine-maintained meiotic arrest. A noinhibition group, composed of NECA and CGS21680, in
which no augmentation of meiotic arrest was observed.
10331459
636
6-formylindolo(3,2-b)carbazole
female gamete generation
increase
preantral ovarian follicle growth
GO:0001546
Homo sapiens
6-formylindolo(3,2-b)carbazole results in increased preantral ovarian follicle growth
29146461
637
Acetyl-aspartyl-glutamyl-valyl-aspartal
female gamete generation
increase
negative regulation of oocyte maturation
GO:1900194
Mus musculus
acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [Silver Compounds results in increased negative regulation of oocyte maturation]
29964317
638
Acyano-4-hydroxy cinnamate (4-CIN)
female gamete generation
decrease
oocyte maturation
GO:0001556
Mus musculus
Percentages of MII oocytes decreased significantly with increasing concentrations of 4-CIN.
26857840
639
Adenine
female gamete generation
related
oogenesis
GO:0048477
Mus musculus
Significantly changed metabolites during meiotic maturation (GV, GVBD, MII) (Metabolomics data: ultra-high-performance liquid chromatography-tandem high-resolution mass spectrometry (UHPLC-HRMS))
33068521
640
Adenosine
female gamete generation
affect
meiotic cell cycle process involved in oocyte maturation
GO:1903537
Mus musculus
Uptake and metabolism of adenosine mediate a meiosis-arresting action on mouse oocytes
10331459
641
Adenosine
female gamete generation
related
oogenesis
GO:0048477
Mus musculus
Significantly changed metabolites during meiotic maturation (GV, GVBD, MII) (Metabolomics data: ultra-high-performance liquid chromatography-tandem high-resolution mass spectrometry (UHPLC-HRMS))
33068521
642
Aflatoxin (AF)
female gamete generation
increase
DNA methylation involved in gamete generation
GO:0043046
Mus musculus
The fluorescence intensity analysis showed that the general DNA methylation levels increased in oocytes from high dose mycotoxin-fed mice.?Mycotoxin-contaminated maize (deoxynivalenol (DON) at 3,875
24288346, 24810297
643
Agmatine Sulfate
female gamete generation
Not
oogenesis
GO:0048477
Mus musculus
Not significantly changed metabolites during meiotic maturation (GV, GVBD, MII) (Metabolomics data: ultra-high-performance liquid chromatography-tandem high-resolution mass spectrometry (UHPLC-HRMS))
33068521
644
Allantoin
female gamete generation
Not
oogenesis
GO:0048477
Mus musculus
Not significantly changed metabolites during meiotic maturation (GV, GVBD, MII) (Metabolomics data: ultra-high-performance liquid chromatography-tandem high-resolution mass spectrometry (UHPLC-HRMS))
33068521
645
Alpha-ketoglutarate
female gamete generation
affect
oogenesis
GO:0009790
Mus musculus
For any questions on the database, please send E-mail to caoyuedi@sjtu.edu.cn.
