Chemicals with Transgenerational Effects on Disease or Function
Show
entries
No.
Chemical Name
GO Biological Process
Effect
Specific BP
GO
Species
Description
PMID
616
3-Methylxanthine
female gamete generation
related
oogenesis
GO:0048477
Mus musculus
Significantly changed metabolites during meiotic maturation (GV, GVBD, MII) (Metabolomics data: ultra-high-performance liquid chromatography-tandem high-resolution mass spectrometry (UHPLC-HRMS))
33068521
617
3-Phenylbutyric Acid
female gamete generation
Not
oogenesis
GO:0048477
Mus musculus
Not significantly changed metabolites during meiotic maturation (GV, GVBD, MII) (Metabolomics data: ultra-high-performance liquid chromatography-tandem high-resolution mass spectrometry (UHPLC-HRMS))
33068521
618
4,4,14
female gamete generation
increase
meiotic cell cycle process involved in oocyte maturation
GO:1903537
Mus musculus
Activity of sterols to significantly induce resumption of meiosis in naked mouse oocytes compared with that of a control without the compound during a 24-h culture period
7700384, 11988327
619
Bisphenol F
female gamete generation
increase
negative regulation of oocyte maturation
GO:1900194
Mus musculus
4,4'-bisphenol F results in increased negative regulation of oocyte maturation
33476676
620
4,4-dimethyl-5
female gamete generation
increase
meiotic cell cycle process involved in oocyte maturation
GO:1903537
Mus musculus
Activity of sterols to significantly induce resumption of meiosis in naked mouse oocytes compared with that of a control without the compound during a 24-h culture period
11988327
621
4,4-dimethyl-5
female gamete generation
increase
meiotic cell cycle process involved in oocyte maturation
GO:1903537
Mus musculus
Activity of sterols to significantly induce resumption of meiosis in naked mouse oocytes compared with that of a control without the compound during a 24-h culture period
11988327
622
4,4-dimethyl-5
female gamete generation
increase
meiotic cell cycle process involved in oocyte maturation
GO:1903537
Mus musculus
Activity of sterols to significantly induce resumption of meiosis in naked mouse oocytes compared with that of a control without the compound during a 24-h culture period
7700384, 11988327
623
4,4-dimethyl-5
female gamete generation
increase
meiotic cell cycle process involved in oocyte maturation
GO:1903537
Mus musculus
Activity of sterols to significantly induce resumption of meiosis in naked mouse oocytes compared with that of a control without the compound during a 24-h culture period
9788247, 11988327
624
4,4-dimethyl-5
female gamete generation
increase
meiotic cell cycle process involved in oocyte maturation
GO:1903537
Mus musculus
Activity of sterols to significantly induce resumption of meiosis in naked mouse oocytes compared with that of a control without the compound during a 24-h culture period
7700384, 11988327
625
4,4-dimethylcholest-5-en-3
female gamete generation
increase
meiotic cell cycle process involved in oocyte maturation
GO:1903537
Mus musculus
Activity of sterols to significantly induce resumption of meiosis in naked mouse oocytes compared with that of a control without the compound during a 24-h culture period
9788247, 11988327
626
4,4-dimethylcholest-8-en-3
female gamete generation
increase
meiotic cell cycle process involved in oocyte maturation
GO:1903537
Mus musculus
Activity of sterols to significantly induce resumption of meiosis in naked mouse oocytes compared with that of a control without the compound during a 24-h culture period
7700384, 11988327
627
4,4-dimethylcholesta-5,7-dien-3
female gamete generation
increase
meiotic cell cycle process involved in oocyte maturation
GO:1903537
Mus musculus
Activity of sterols to significantly induce resumption of meiosis in naked mouse oocytes compared with that of a control without the compound during a 24-h culture period
9788247, 11988327
628
4,4-dimethylcholesta-8,14-dien-3
female gamete generation
increase
meiotic cell cycle process involved in oocyte maturation
GO:1903537
Mus musculus
Activity of sterols to significantly induce resumption of meiosis in naked mouse oocytes compared with that of a control without the compound during a 24-h culture period
7700384, 11988327
629
4,4'-hexafluorisopropylidene diphenol
female gamete generation
decrease
primary ovarian follicle growth involved in double layer follicle stage
GO:0043929
Mus musculus
4,4'-hexafluorisopropylidene diphenol results in decreased primary ovarian follicle growth involved in double layer follicle stage
30675821
630
4-Methylcatechol
female gamete generation
Not
oogenesis
GO:0048477
Mus musculus
Not significantly changed metabolites during meiotic maturation (GV, GVBD, MII) (Metabolomics data: ultra-high-performance liquid chromatography-tandem high-resolution mass spectrometry (UHPLC-HRMS))
33068521
For any questions on the database, please send E-mail to caoyuedi@sjtu.edu.cn.
