Chemicals with Transgenerational Effects on Disease or Function

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No. Chemical Name GO Biological Process Effect Specific BP GO Species Description PMID
436L-Prolineembryo developmentrelatedembryo developmentGO:0009790Mus musculusSignificantly changed metabolites in the two-cell-like cell (2CLC) compared with ES cells (ESCs) samples (Metabolomics data: liquid chromatography34428399
437L-Prolineembryo developmentrelatedembryo developmentGO:0009790Mus musculusHigher in the blastocyst-stage embryos compared with two-cell embryos (Metabolomics data: liquid chromatography34650276
438Propylene Glycolembryo developmentaffectregulation of gastrulationGO:0010470Mus musculusPropylene Glycol affects regulation of gastrulation28184906
439Purineembryo developmentrelatedembryo developmentGO:0009790Mus musculusSignificantly changed metabolites in the two-cell-like cell (2CLC) compared with ES cells (ESCs) samples (Metabolomics data: liquid chromatography34428399
440Purineembryo developmentrelatedembryo developmentGO:0009790Mus musculusMetabolite dynamics during mouse embryo development (Zygote, 2-cell, 4-cell, 8-cell, Morula, Blastocyst) (Metabolomics data: ultra-high-performance liquid chromatography coupled with hybrid quadrupole time-of-flight mass spectrometry (UHPLC36167681
441Pyridoxamineembryo developmentrelatedembryo developmentGO:0009790Mus musculusHigher in the blastocyst-stage embryos compared with two-cell embryos (Metabolomics data: liquid chromatography34650276
442Pyridoxineembryo developmentrelatedembryo developmentGO:0009790Mus musculusSignificantly changed metabolites in the two-cell-like cell (2CLC) compared with ES cells (ESCs) samples (Metabolomics data: liquid chromatography34428399
443Pyroglutamateembryo developmentrelatedembryo developmentGO:0009790Mus musculusHigher in the blastocyst-stage embryos compared with two-cell embryos (Metabolomics data: liquid chromatography34650276
444Pyruvaldehydeembryo developmentdecreaseinner cell mass cell proliferationGO:0001833Mus musculusPyruvaldehyde results in decreased inner cell mass cell proliferation21793156
445Pyruvaldehydeembryo developmentdecreaseembryo developmentGO:0009790Mus musculusPyruvaldehyde results in decreased embryo development21793156
446Pyruvateembryo developmentrelatedembryo developmentGO:0009790Mus musculusHigher in the blastocyst-stage embryos compared with two-cell embryos (Metabolomics data: liquid chromatography34650276
447pyruvateembryo developmentaffectembryo developmentGO:0009790Mus musculusNuclear TCA proteins and metabolites are essential for zygotic genome activation (ZGA) Pyruvate, O-glycosylation, and chaperones are essential for this nuclear localization?28086092
448pyruvateembryo developmentaffectembryo developmentGO:0009790Mus musculusLactate and pyruvate together are able to support normal development of 1-cell F2 embryos to the morula stage in vitro.1769345, 1518005
449pyruvateembryo developmentaffectembryo developmentGO:0009790Homo sapiensNuclear TCA proteins and metabolites are essential for zygotic genome activation (ZGA) Pyruvate, O-glycosylation, and chaperones are essential for this nuclear localization?28086092
450pyruvateembryo developmentaffectembryo developmentGO:0009790Homo sapiensPyruvate is an essential component of the culture media for human embryos.8283458

Showing 436 to 450 of 1481 entries

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Copyright © Haifeng Chen Lab, Shanghai Jiao Tong University.