Chemicals with Transgenerational Effects on Disease or Function

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No. Chemical Name GO Biological Process Effect Specific BP GO Species Description PMID
406Pantothenic acidembryo developmentrelatedembryo developmentGO:0009790Mus musculusHigher in the blastocyst-stage embryos compared with two-cell embryos (Metabolomics data: liquid chromatography34650276
407Pantothenic acidembryo developmentrelatedembryo developmentGO:0009790Mus musculusSignificantly changed metabolites in the two-cell-like cell (2CLC) compared with ES cells (ESCs) samples (Metabolomics data: liquid chromatography34428399
408PD0325901embryo developmentaffectembryo developmentGO:0009790Homo sapiensPD0325901 is one of optimized small molecule inhibitor cocktail supports long-term maintenance of human embryonic stem cells21266967
409PD173074embryo developmentaffectembryo developmentGO:0009790Homo sapiensPD173074 is one of optimized small molecule inhibitor cocktail supports long-term maintenance of human embryonic stem cells21266967
410PD98059?embryo developmentaffectembryo developmentGO:0009790Homo sapiensPD98059 is one of optimized small molecule inhibitor cocktail supports long-term maintenance of human embryonic stem cells21266967
411Pentadecanalembryo developmentrelatedembryo developmentGO:0009790Mus musculusMetabolite dynamics during mouse embryo development (Zygote, 2-cell, 4-cell, 8-cell, Morula, Blastocyst) (Metabolomics data: ultra-high-performance liquid chromatography coupled with hybrid quadrupole time-of-flight mass spectrometry (UHPLC36167681
412pentoxifyllineembryo developmentdecreaseembryo developmentGO:0009790Mus musculusIf PTX was not washed out, fertilization was reduced significantly, yet development of fertilized oocytes was unaffected. If insemination was performed in the presence of PTX both fertilization and development were impaired. 7844224
413pentoxifyllineembryo developmentdecreaseembryo developmentGO:0009790Mus musculusIf sperm were treated by both pentoxifylline and 2-deoxyadenosine before insemination of postovulatory mouse oocytes, two-cell embryo formation was found to be reduced even if both agents were eluted from the sperm before insemination.?8062965
414pentoxifyllineembryo developmentincreaseembryo developmentGO:0009790Mus musculusSignificantly higher percentage of zygotes progressed to two-cell stage in both biotin (P?30284103
415perfluorodecanoic acidembryo developmentaffectDNA methylation involved in embryo developmentGO:0043045Homo sapiens[Environmental Pollutants results in increased abundance of perfluorodecanoic acid] which affects DNA methylation involved in embryo development32653021
416perfluorodecanoic acidembryo developmentaffectembryonic placenta morphogenesisGO:0060669Homo sapiensperfluorodecanoic acid affects embryonic placenta morphogenesis33677611
417perfluorohexanesulfonic acidembryo developmentaffectembryonic placenta morphogenesisGO:0060669Homo sapiensperfluorohexanesulfonic acid affects embryonic placenta morphogenesis33677611
418perfluoro-n-heptanoic acidembryo developmentaffectembryonic placenta morphogenesisGO:0060669Homo sapiensperfluoro-n-heptanoic acid affects embryonic placenta morphogenesis33677611
419perfluorooctane sulfonic acidembryo developmentaffectDNA methylation involved in embryo developmentGO:0043045Homo sapiens[Environmental Pollutants results in increased abundance of perfluorooctane sulfonic acid] which affects DNA methylation involved in embryo development32653021
420perfluorooctanesulfonamideembryo developmentaffectembryonic placenta morphogenesisGO:0060669Homo sapiensperfluorooctanesulfonamide affects embryonic placenta morphogenesis33677611

Showing 406 to 420 of 1481 entries

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Copyright © Haifeng Chen Lab, Shanghai Jiao Tong University.