Chemicals with Transgenerational Effects on Disease or Function

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No. Chemical Name GO Biological Process Effect Specific BP GO Species Description PMID
376NADembryo developmentrelatedembryo developmentGO:0009790Mus musculusMetabolite dynamics during mouse embryo development (Zygote, 2-cell, 4-cell, 8-cell, Morula, Blastocyst) (Metabolomics data: ultra-high-performance liquid chromatography coupled with hybrid quadrupole time-of-flight mass spectrometry (UHPLC36167681
377NAD+embryo developmentincreaseembryo developmentGO:0009790Homo sapiensNAD+ supplement promotes the removal of zygotic H3K27ac and benefits preimplantation development of human embryos36167681
378NADPembryo developmentrelatedembryo developmentGO:0009790Mus musculusSignificantly changed metabolites in the two-cell-like cell (2CLC) compared with ES cells (ESCs) samples (Metabolomics data: liquid chromatography34428399
379NADP+embryo developmentrelatedembryo developmentGO:0009790Mus musculusMetabolite dynamics during mouse embryo development (Zygote, 2-cell, 4-cell, 8-cell, Morula, Blastocyst) (Metabolomics data: ultra-high-performance liquid chromatography coupled with hybrid quadrupole time-of-flight mass spectrometry (UHPLC36167681
380Nicotinamideembryo developmentrelatedembryo developmentGO:0009790Mus musculusSignificantly changed metabolites in the two-cell-like cell (2CLC) compared with ES cells (ESCs) samples (Metabolomics data: liquid chromatography34428399
381Nicotinamideembryo developmentrelatedembryo developmentGO:0009790Mus musculusHigher in the blastocyst-stage embryos compared with two-cell embryos (Metabolomics data: liquid chromatography34650276
382Nicotinamide ribotideembryo developmentrelatedembryo developmentGO:0009790Mus musculusMetabolite dynamics during mouse embryo development (Zygote, 2-cell, 4-cell, 8-cell, Morula, Blastocyst) (Metabolomics data: ultra-high-performance liquid chromatography coupled with hybrid quadrupole time-of-flight mass spectrometry (UHPLC36167681
383Nicotinate ribonucleotideembryo developmentrelatedembryo developmentGO:0009790Mus musculusMetabolite dynamics during mouse embryo development (Zygote, 2-cell, 4-cell, 8-cell, Morula, Blastocyst) (Metabolomics data: ultra-high-performance liquid chromatography coupled with hybrid quadrupole time-of-flight mass spectrometry (UHPLC36167681
384nilotinibembryo developmentaffectregulation of gastrulationGO:0010470Mus musculusnilotinib affects regulation of gastrulation28184906
385nitric oxideembryo developmentdecreaseembryo developmentGO:0009790Homo sapiensNO may inhibit embryo development through a cGMP-independent pathway.11369599
386nonachlorembryo developmentaffectDNA methylation involved in embryo developmentGO:0043045Homo sapiens[[Environmental Pollutants results in increased abundance of Pesticides] which results in increased abundance of nonachlor] which affects DNA methylation involved in embryo development32653021
387norfluoxetineembryo developmentdecreaseembryonic morphogenesisGO:0048598Mus musculusnorfluoxetine results in decreased embryonic morphogenesis29893963
388ochratoxin A (OTA)embryo developmentaffectembryo developmentGO:0009790Mus musculusOchratoxin a inhibits mouse embryonic development by activating a mitochondrion-dependent apoptotic signaling pathway.23296271
389ochratoxin A (OTA)embryo developmentaffectembryo developmentGO:0009790Mus musculusAlternariol (AOH) and ochratoxin A (OTA), two mycotoxins found in many foods worldwide, exhibit cytotoxicity and embryotoxicity, triggering apoptosis and cell cycle arrest in several mammalian cells and mouse embryos. 34956623
390ochratoxin A (OTA)embryo developmentaffectembryo developmentGO:0009790Mus musculusPrevention of ochratoxin A-induced oxidative stress-mediated apoptotic processes and impairment of embryonic development in mouse blastocysts by liquiritigenin30698892, 34956623

Showing 376 to 390 of 1481 entries

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Copyright © Haifeng Chen Lab, Shanghai Jiao Tong University.