Chemicals with Transgenerational Effects on Disease or Function

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No. Chemical Name GO Biological Process Effect Specific BP GO Species Description PMID
361n-3 PUFAembryo developmentaffectembryonic morphogenesisGO:0048598Mus musculusExposure of oocytes to an environment high in n-3 PUFA during in vivo fertilization adversely affected the morphological appearance of the embryo.18073322
362n-3 PUFAembryo developmentdecreaseembryo developmentGO:0009790Mus musculusHigh maternal dietary n-3 PUFA exposure periconception reduces normal embryo development in the mouse and is associated with perturbed mitochondrial metabolism.18073322
363n-3 PUFAembryo developmentdecreaseembryo developmentGO:0009790Mus musculushigh maternal dietary n-3 PUFA exposure periconception reduces normal embryo development in the mouse and is associated with perturbed mitochondrial metabolism.18073322
364n-3 PUFA embryo developmentdecreaseembryo developmentGO:0009790Mus musculusCulture of mouse embryos with both n-3 and n-6 PUFAs increased lipid peroxidation and decreased embryo development, which was attenuated by the addition of antioxidants 7633171, 18073322
365n-6 PUFAembryo developmentdecreaseembryo developmentGO:0009790Mus musculusculture of mouse embryos with both n-3 and n-6 PUFAs increased lipid peroxidation and decreased embryo development, which was attenuated by the addition of antioxidants7633171, 18073322
366NAADembryo developmentrelatedembryo developmentGO:0009790Mus musculusSignificantly changed metabolites in the two-cell-like cell (2CLC) compared with ES cells (ESCs) samples (Metabolomics data: liquid chromatography34428399
367N-Acetyl Lalanineembryo developmentrelatedembryo developmentGO:0009790Mus musculusHigher in the blastocyst-stage embryos compared with two-cell embryos (Metabolomics data: liquid chromatography34650276
368N-Acetyl-Asp-Gluembryo developmentrelatedembryo developmentGO:0009790Mus musculusHigher in the blastocyst-stage embryos compared with two-cell embryos (Metabolomics data: liquid chromatography34650276
369N-Acetyl-L-Cysteineembryo developmentincreaseembryo developmentGO:0009790Mus musculusthe antioxidant combination Acetyl-L-Carnitine, N-Acetyl-L-Cysteine and 29136144, 27165621
370N-Acetyl-L-glutamineembryo developmentrelatedembryo developmentGO:0009790Mus musculusHigher in the blastocyst-stage embryos compared with two-cell embryos (Metabolomics data: liquid chromatography34650276
371N-Acetyl-L-lysineembryo developmentrelatedembryo developmentGO:0009790Mus musculusHigher in the blastocyst-stage embryos compared with two-cell embryos (Metabolomics data: liquid chromatography34650276
372N-acetyl-methionineembryo developmentrelatedembryo developmentGO:0009790Mus musculusMetabolite dynamics during mouse embryo development (Zygote, 2-cell, 4-cell, 8-cell, Morula, Blastocyst) (Metabolomics data: ultra-high-performance liquid chromatography coupled with hybrid quadrupole time-of-flight mass spectrometry (UHPLC36167681
373N-Acetylputrescineembryo developmentrelatedembryo developmentGO:0009790Mus musculusSignificantly changed metabolites in the two-cell-like cell (2CLC) compared with ES cells (ESCs) samples (Metabolomics data: liquid chromatography34428399
374N-Acetylputrescineembryo developmentrelatedembryo developmentGO:0009790Mus musculusHigher in the blastocyst-stage embryos compared with two-cell embryos (Metabolomics data: liquid chromatography34650276
375NADembryo developmentrelatedembryo developmentGO:0009790Mus musculusHigher in the blastocyst-stage embryos compared with two-cell embryos (Metabolomics data: liquid chromatography34650276

Showing 361 to 375 of 1481 entries

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Copyright © Haifeng Chen Lab, Shanghai Jiao Tong University.