Chemicals with Transgenerational Effects on Disease or Function

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No. Chemical Name GO Biological Process Effect Specific BP GO Species Description PMID
331Lysophosphatidic acidembryo developmentincreaseembryo developmentGO:0009790Homo sapiensLysophosphatidic Acid is abundant in seminal plasma and follicular fluid. It promotes early embryonic development and embryo implantation.35903269?
332Lysophosphatidylcholineembryo developmentrelateembryo developmentGO:0009790Mus musculusMany peaks were detected from a raster scan of the whole embryonic sections. The peaks at?m/z were identified by MS/MS analyses as lysophosphatidylcholine (LysoPtdCho). 19685253
333Malateembryo developmentrelatedembryo developmentGO:0009790Mus musculusSignificantly changed metabolites in the two-cell-like cell (2CLC) compared with ES cells (ESCs) samples (Metabolomics data: liquid chromatography34428399
334Malateembryo developmentrelatedembryo developmentGO:0009790Mus musculusHigher in the blastocyst-stage embryos compared with two-cell embryos (Metabolomics data: liquid chromatography34650276
335Malateembryo developmentrelatedembryo developmentGO:0009790Mus musculusMetabolite dynamics during mouse embryo development (Zygote, 2-cell, 4-cell, 8-cell, Morula, Blastocyst) (Metabolomics data: ultra-high-performance liquid chromatography coupled with hybrid quadrupole time-of-flight mass spectrometry (UHPLC36167681
336Melatoninembryo developmentrelatedembryo developmentGO:0009790Mus musculusSignificantly changed metabolites in the two-cell-like cell (2CLC) compared with ES cells (ESCs) samples (Metabolomics data: liquid chromatography34428399
337Melatoninembryo developmentincreaseembryo developmentGO:0009790Homo sapiensMelatonin promotes human early embryo development 31361919
338metabisulfiteembryo developmentdecreaseembryonic morphogenesisGO:0048598Mus musculusmetabisulfite results in decreased embryonic morphogenesis28927898
339Metforminembryo developmentincreaseembryo developmentGO:0009790Mus musculusmetformin treatment of oocytes from aged mice can apparently improve early embryonic development.36393869
340Methionineembryo developmentrelatedembryo developmentGO:0009790Mus musculusSignificantly changed metabolites in the two-cell-like cell (2CLC) compared with ES cells (ESCs) samples (Metabolomics data: liquid chromatography34428399
341Methionineembryo developmentrelatedembryo developmentGO:0009790Mus musculusMetabolite dynamics during mouse embryo development (Zygote, 2-cell, 4-cell, 8-cell, Morula, Blastocyst) (Metabolomics data: ultra-high-performance liquid chromatography coupled with hybrid quadrupole time-of-flight mass spectrometry (UHPLC36167681
342Methionineembryo developmentrelatedembryo developmentGO:0009790Mus musculusOmission of lysine, methionine, phenylalanine, tryptophane and tyrosine from the culture medium markedly reduced blastocyst outgrowth, but did not inhibit it completely; while omission of isolecine and valine reduced the extent of outgrowth only slightly. Gwatkin, R. B. L. (1966). Amino acid requirements for attachment and outgrowth of the mouse blastocyst in vitro.?Journal of Cellular Physiology,?68(3), 335-343.
343Methionine S-oxideembryo developmentrelatedembryo developmentGO:0009790Mus musculusMetabolite dynamics during mouse embryo development (Zygote, 2-cell, 4-cell, 8-cell, Morula, Blastocyst) (Metabolomics data: ultra-high-performance liquid chromatography coupled with hybrid quadrupole time-of-flight mass spectrometry (UHPLC36167681
344Methionine sulfoxideembryo developmentrelatedembryo developmentGO:0009790Mus musculusHigher in the blastocyst-stage embryos compared with two-cell embryos (Metabolomics data: liquid chromatography34650276
345Methoxyacetic acidembryo developmentaffectregulation of gastrulationGO:0010470Mus musculusmethoxyacetic acid affects regulation of gastrulation28184906

Showing 331 to 345 of 1481 entries

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Copyright © Haifeng Chen Lab, Shanghai Jiao Tong University.