Chemicals with Transgenerational Effects on Disease or Function

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No. Chemical Name GO Biological Process Effect Specific BP GO Species Description PMID
226Fipronilembryo developmentdecreaseembryo developmentGO:0009790Mus musculusFipronil results in decreased embryo development30130558
227Flame Retardantsembryo developmentaffectembryonic placenta morphogenesisGO:0060669Homo sapiens[Flame Retardants results in increased abundance of bis(1,3-dichloropropyl)phosphate] which affects embryonic placenta morphogenesis33677611
228Fluorouracilembryo developmentdecreaseembryo developmentGO:0009790Mus musculusFluorouracil results in decreased embryo development26178269
229Fluorouracilembryo developmentdecreaseembryonic morphogenesisGO:0048598Mus musculusFluorouracil results in decreased embryonic morphogenesis26385866
230Fluorouracilembryo developmentdecreaseneural tube developmentGO:0021915Mus musculusFluorouracil results in decreased neural tube development29258758
231Fluoxetineembryo developmentdecreaseembryonic morphogenesisGO:0048598Mus musculusFluoxetine results in decreased embryonic morphogenesis29893963
232Folic Acidembryo developmentrelatedembryo developmentGO:0009790Mus musculusMetabolite dynamics during mouse embryo development (Zygote, 2-cell, 4-cell, 8-cell, Morula, Blastocyst) (Metabolomics data: ultra-high-performance liquid chromatography coupled with hybrid quadrupole time-of-flight mass spectrometry (UHPLC36167681
233Folic Acidembryo developmentaffectembryo developmentGO:0009790Homo sapiensMicronutrient (folate, B12, B6) deficiencies or insufficiency could influence fetal growth by their effect on folate/methionine metabolism in the mother and the fetus.22418620
234Folic Acidembryo developmentaffectembryo developmentGO:0009790Mus musculusFolic Acid deficiency results in decreased embryo development20534379
235Folic Acidembryo developmentaffectneural tube closureGO:0001843Mus musculusFolic Acid deficiency results in decreased neural tube closure20534379
236Folic acidembryo developmentrelatedembryo developmentGO:0009790Mus musculusSignificantly changed metabolites in the two-cell-like cell (2CLC) compared with ES cells (ESCs) samples (Metabolomics data: liquid chromatography34428399
237folic acidembryo developmentdecreaseembryo developmentGO:0009790Homo sapiensUsing human induced pluripotent stem cell (hiPSC)-derived embryoid bodies (EB) as an in vitro model to investigate the embryotoxic effects of a carefully selected set of pharmacological compounds. The results showed that the compounds differentially repressed cell growth, compromised morphology, and triggered apoptosis in the EBs.34742744
238forskolinembryo developmentdecreaseembryo developmentGO:0009790Mus musculusan adenylate cyclase stimulator, forskolin, inhibits cardiomyocyte differentiation in mouse ES cells17979183?
239Fructose 1,6-bisphosphateembryo developmentrelatedembryo developmentGO:0009790Mus musculusMetabolite dynamics during mouse embryo development (Zygote, 2-cell, 4-cell, 8-cell, Morula, Blastocyst) (Metabolomics data: ultra-high-performance liquid chromatography coupled with hybrid quadrupole time-of-flight mass spectrometry (UHPLC36167681
240Fructose 2,6-bisphosphateembryo developmentrelatedembryo developmentGO:0009790Mus musculusMetabolite dynamics during mouse embryo development (Zygote, 2-cell, 4-cell, 8-cell, Morula, Blastocyst) (Metabolomics data: ultra-high-performance liquid chromatography coupled with hybrid quadrupole time-of-flight mass spectrometry (UHPLC36167681

Showing 226 to 240 of 1481 entries

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Copyright © Haifeng Chen Lab, Shanghai Jiao Tong University.