Chemicals with Transgenerational Effects on Disease or Function

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No. Chemical Name GO Biological Process Effect Specific BP GO Species Description PMID
181Diethylstilbestrolembryo developmentdecreaseembryonic placenta morphogenesisGO:0060669Mus musculusDiethylstilbestrol affects embryonic placenta morphogenesis22733484
182Diethylstilbestrolembryo developmentdecreaseembryonic morphogenesisGO:0048598Mus musculusDiethylstilbestrol results in decreased embryonic morphogenesis26385866
183Diethylstilbestrolembryo developmentdecreaseembryonic morphogenesisGO:0048598Mus musculusDiethylstilbestrol results in decreased embryonic morphogenesis29990529
184Diethylstilbestrolembryo developmentdecreaseembryo developmentGO:0009790Mus musculusHatching was inhibited in mouse embryos cultured in diethylstilbestrol.Suppressed development of cultured mouse and swine embryos by diethylstilbestrol
185Dihydrofolic acidembryo developmentrelatedembryo developmentGO:0009790Mus musculusMetabolite dynamics during mouse embryo development (Zygote, 2-cell, 4-cell, 8-cell, Morula, Blastocyst) (Metabolomics data: ultra-high-performance liquid chromatography coupled with hybrid quadrupole time-of-flight mass spectrometry (UHPLC36167681
186Dihydroxyacetone Phosphate Acyl Esterembryo developmentrelatedembryo developmentGO:0009790Mus musculusMetabolite dynamics during mouse embryo development (Zygote, 2-cell, 4-cell, 8-cell, Morula, Blastocyst) (Metabolomics data: ultra-high-performance liquid chromatography coupled with hybrid quadrupole time-of-flight mass spectrometry (UHPLC36167681
187Diisobutyl phthalateembryo developmentdecreaseembryo developmentGO:0009790Mus musculus[Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with Dibutyl Phthalate co-treated with diethyl phthalate co-treated with butylbenzyl phthalate] results in decreased embryo development33711355
188Diisodecyl phthalateembryo developmentdecreaseembryo developmentGO:0009790Mus musculus[Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with Dibutyl Phthalate co-treated with diethyl phthalate co-treated with butylbenzyl phthalate] results in decreased embryo development33711355
189Dimethyl sulfoxide (DMSO)embryo developmentincreasegrowth involved in heart morphogenesisGO:0003241Mus musculusDimethyl sulfoxide (DMSO) is a commonly used cryoprotectant that also induces cardiomyogenic differentiation in ES cells.17979183?
190Dimethyl sulfoxide (DMSO)embryo developmentincreasegrowth involved in heart morphogenesisGO:0003241Mus musculusDimethyl sulfoxide (DMSO) is a commonly used cryoprotectant that also induces cardiomyogenic differentiation in embryonal carcinoma cells.17979183?
191Dimethyl sulfoxide (DMSO)embryo developmentincreasegrowth involved in heart morphogenesisGO:0003241Mus musculusDimethyl sulfoxide (DMSO) induces the expression of cardiac specific transcription factors GATA-4 and Nkx2.5, and increases intracellular Ca2+ levels 8507558, 8393876, 9857019, 10478795, 10926868, 17979183
192Dimethyl sulfoxide (DMSO)embryo developmentnotheart morphogenesisGO:0003007Homo sapiensHuman ES cells indicated that cardiomyocyte differentiation in human ES cells was not affected by Dimethyl sulfoxide (DMSO).12242268, 17979183
193Dimethylarsinous acidembryo developmentdecreaseneural crest cell fate specificationGO:0014036Mus musculusDimethylarsinous acid results in decreased neural crest cell fate specification26024302
194Dolutegravirembryo developmentdecreaseembryonic morphogenesisGO:0048598Mus musculusdolutegravir results in decreased embryonic morphogenesis34515794
195Dolutegravirembryo developmentdecreaseembryonic morphogenesisGO:0048598Mus musculusdolutegravir results in decreased embryonic morphogenesis34515794

Showing 181 to 195 of 1481 entries

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Copyright © Haifeng Chen Lab, Shanghai Jiao Tong University.