Chemicals with Transgenerational Effects on Disease or Function
Show
entries
No.
Chemical Name
GO Biological Process
Effect
Specific BP
GO
Species
Description
PMID
121
Carnitine-C18
embryo development
related
embryo development
GO:0009790
Mus musculus
Significantly changed metabolites in the two-cell-like cell (2CLC) compared with ES cells (ESCs) samples (Metabolomics data: liquid chromatography
34428399
122
Carnitine-C18
embryo development
related
embryo development
GO:0009790
Mus musculus
Higher in the blastocyst-stage embryos compared with two-cell embryos (Metabolomics data: liquid chromatography
34650276
123
Carnitine-C3
embryo development
related
embryo development
GO:0009790
Mus musculus
Significantly changed metabolites in the two-cell-like cell (2CLC) compared with ES cells (ESCs) samples (Metabolomics data: liquid chromatography
34428399
124
Carnitine-C3
embryo development
related
embryo development
GO:0009790
Mus musculus
Higher in the blastocyst-stage embryos compared with two-cell embryos (Metabolomics data: liquid chromatography
34650276
125
Carnitine-C4
embryo development
related
embryo development
GO:0009790
Mus musculus
Significantly changed metabolites in the two-cell-like cell (2CLC) compared with ES cells (ESCs) samples (Metabolomics data: liquid chromatography
34428399
126
Carnitine-C5
embryo development
related
embryo development
GO:0009790
Mus musculus
Significantly changed metabolites in the two-cell-like cell (2CLC) compared with ES cells (ESCs) samples (Metabolomics data: liquid chromatography
34428399
127
Carnitine-C5
embryo development
related
embryo development
GO:0009790
Mus musculus
Higher in the blastocyst-stage embryos compared with two-cell embryos (Metabolomics data: liquid chromatography
34650276
128
Carnitine-C6
embryo development
related
embryo development
GO:0009790
Mus musculus
Significantly changed metabolites in the two-cell-like cell (2CLC) compared with ES cells (ESCs) samples (Metabolomics data: liquid chromatography
34428399
129
Carnitine-C6
embryo development
related
embryo development
GO:0009790
Mus musculus
Higher in the blastocyst-stage embryos compared with two-cell embryos (Metabolomics data: liquid chromatography
34650276
130
Carnitine-C8
embryo development
related
embryo development
GO:0009790
Mus musculus
Significantly changed metabolites in the two-cell-like cell (2CLC) compared with ES cells (ESCs) samples (Metabolomics data: liquid chromatography
34428399
131
Carnitine-C8
embryo development
related
embryo development
GO:0009790
Mus musculus
Higher in the blastocyst-stage embryos compared with two-cell embryos (Metabolomics data: liquid chromatography
34650276
132
Ceramide
embryo development
decrease
blastocyst development
GO:0001824
Mus musculus
Ceramide decreases the blastocyst formation rate and induces embryonic cell apoptosis.
23731666
133
CH5183284
embryo development
decrease
clearance of cells from fusion plate
GO:0060884
Homo sapiens
CH5183284 results in decreased clearance of cells from fusion plate
28898253
134
Chir 99021
embryo development
increase
neural plate development
GO:0001840
Homo sapiens
[[Chir 99021 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with Tretinoin] affects cell differentiation] which results in increased neural plate development
31711903
135
Chir 99021
embryo development
increase
endodermal cell differentiation
GO:0035987
Homo sapiens
[Chir 99021 affects cell differentiation] which results in increased endodermal cell differentiation
31711903
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