Chemicals with Transgenerational Effects on Disease or Function

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No. Chemical Name GO Biological Process Effect Specific BP GO Species Description PMID
136Chir 99021embryo developmentaffectembryo developmentGO:0009790Homo sapiensChir 99021 is one of optimized small molecule inhibitor cocktail supports long-term maintenance of human embryonic stem cells21266967
137Chlordeconeembryo developmentaffectembryo developmentGO:0009790Mus musculusgestational exposure to low dose of CD leads to oxidative stress and affects meiosis and gene expression in embryonic ovaries.?31084621
138Cholesteryl sulfateembryo developmentrelatedembryo developmentGO:0009790Mus musculusMetabolite dynamics during mouse embryo development (Zygote, 2-cell, 4-cell, 8-cell, Morula, Blastocyst) (Metabolomics data: ultra-high-performance liquid chromatography coupled with hybrid quadrupole time-of-flight mass spectrometry (UHPLC36167681
139Cholineembryo developmentrelatedembryo developmentGO:0009790Mus musculusSignificantly changed metabolites in the two-cell-like cell (2CLC) compared with ES cells (ESCs) samples (Metabolomics data: liquid chromatography34428399
140Cholineembryo developmentrelatedembryo developmentGO:0009790Mus musculusMetabolite dynamics during mouse embryo development (Zygote, 2-cell, 4-cell, 8-cell, Morula, Blastocyst) (Metabolomics data: ultra-high-performance liquid chromatography coupled with hybrid quadrupole time-of-flight mass spectrometry (UHPLC36167681
141Citraconateembryo developmentrelatedembryo developmentGO:0009790Mus musculusHigher in the blastocyst-stage embryos compared with two-cell embryos (Metabolomics data: liquid chromatography34650276
142Citrateembryo developmentrelatedembryo developmentGO:0009790Mus musculusHigher in the blastocyst-stage embryos compared with two-cell embryos (Metabolomics data: liquid chromatography34650276
143Citrullineembryo developmentrelatedembryo developmentGO:0009790Mus musculusMetabolite dynamics during mouse embryo development (Zygote, 2-cell, 4-cell, 8-cell, Morula, Blastocyst) (Metabolomics data: ultra-high-performance liquid chromatography coupled with hybrid quadrupole time-of-flight mass spectrometry (UHPLC36167681
144Clothianidinembryo developmentdecreaseblastocyst developmentGO:0001824Mus musculusclothianidin results in decreased blastocyst development29061322
145Clothianidinembryo developmentdecreaseembryonic cleavageGO:0040016Mus musculusclothianidin results in decreased embryonic cleavage29061322
146CMPembryo developmentrelatedembryo developmentGO:0009790Mus musculusSignificantly changed metabolites in the two-cell-like cell (2CLC) compared with ES cells (ESCs) samples (Metabolomics data: liquid chromatography34428399
147CMPembryo developmentrelatedembryo developmentGO:0009790Mus musculusHigher in the blastocyst-stage embryos compared with two-cell embryos (Metabolomics data: liquid chromatography34650276
148Coalembryo developmentincreaseneural tube developmentGO:0021915Homo sapiensCoal results in increased abundance of Smoke which results in increased abundance of Air Pollutants which results in decreased neural tube development24307569
149Coenzyme Q10embryo developmentincreaseembryo developmentGO:0009790Mus musculuscoenzyme Q10 inhibits the reaction [Cyclophosphamide results in decreased embryo development]31557371
150Creatineembryo developmentrelatedembryo developmentGO:0009790Mus musculusHigher in the blastocyst-stage embryos compared with two-cell embryos (Metabolomics data: liquid chromatography34650276

Showing 136 to 150 of 1481 entries

For any questions on the database, please send E-mail to caoyuedi@sjtu.edu.cn.

Copyright © Haifeng Chen Lab, Shanghai Jiao Tong University.