Chemicals with Transgenerational Effects on Disease or Function

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No. Chemical Name GO Biological Process Effect Specific BP GO Species Description PMID
1156Bumetanidemale gamete generationdecreasesperm capacitationGO:0048240Mus musculusbumetanide and furosemide, two blockers of Na(+)/K(+)/Cl(-) cotransporters (NKCC), inhibited all capacitation-associated events, suggesting that these transporters may mediate Cl(-) movements in sperm. 18957426
1157Busulfanmale gamete generationaffectspermatogenesisGO:0007283Mus musculusBusulfan affects spermatogenesis32416107
1158Busulfanmale gamete generationaffectspermatogenesisGO:0007283Mus musculusferrostatin-1 inhibits the reaction [Busulfan affects spermatogenesis]32416107
1159Busulfanmale gamete generationaffectspermatogenesisGO:0007283Mus musculusDeferoxamine inhibits the reaction [Busulfan affects spermatogenesis]32416107
1160Busulfanmale gamete generationaffectspermatogenesisGO:0007283Mus musculussulforaphane inhibits the reaction [Busulfan affects spermatogenesis]32416107
1161Busulfanmale gamete generationaffectspermatogenesisGO:0007283Mus musculusBusulfan affects spermatogenesis35533795
1162Busulfanmale gamete generationaffectspermatogenesisGO:0007283Mus musculusBusulfan affects spermatogenesis35533795
1163Busulfanmale gamete generationdecreaespermatogenesisGO:0007283Mus musculusIn 1994, Brinster etc. firstly established the azoospermia mice model by busulfan injection, which laid a foundation for the further study in spermatogenesis27806317, 7972054, 7972053
1164Busulfanmale gamete generationdecreasespermatogenesisGO:0007283Homo sapiensBusulfan results in decreased spermatogenesis1058559
1165Butylated hydroxyanisolemale gamete generationaffectpositive regulation of flagellated sperm motility involved in capacitationGO:0060474Homo sapiensProtective effect of butylated hydroxytoluene on sperm function in human spermatozoa cryopreserved by vitrification technique24612426
1166Butylbenzyl phthalatemale gamete generationdecreasespermatogenesisGO:0007283Mus musculus[Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in decreased spermatogenesis29029336
1167Butylbenzyl phthalatemale gamete generationdecreasespermatogenesisGO:0007283Mus musculus[Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diethyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in decreased spermatogenesis30802670
1168Butylbenzyl phthalatemale gamete generationdecreasespermatid developmentGO:0007286Mus musculus[Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diethyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate co-treated with diisononyl phthalate] results in decreased spermatid development30802670
1169Butylbenzyl phthalatemale gamete generationdecreasesperm capacitationGO:0048240Mus musculus[Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with Dibutyl Phthalate co-treated with diethyl phthalate co-treated with butylbenzyl phthalate] results in increased sperm capacitation33711355
1170Cadmiummale gamete generationdecreasespermatogenesisGO:0007283Mus musculusCadmium affects spermatogenesis31491373

Showing 1156 to 1170 of 1481 entries

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Copyright © Haifeng Chen Lab, Shanghai Jiao Tong University.