Chemicals with Transgenerational Effects on Disease or Function
Show
entries
No.
Chemical Name
GO Biological Process
Effect
Specific BP
GO
Species
Description
PMID
886
N-Alpha-acetyllysine
female gamete generation
Not
oogenesis
GO:0048477
Mus musculus
Not significantly changed metabolites during meiotic maturation (GV, GVBD, MII) (Metabolomics data: ultra-high-performance liquid chromatography-tandem high-resolution mass spectrometry (UHPLC-HRMS))
33068521
887
Neopterin
female gamete generation
Not
oogenesis
GO:0048477
Mus musculus
Not significantly changed metabolites during meiotic maturation (GV, GVBD, MII) (Metabolomics data: ultra-high-performance liquid chromatography-tandem high-resolution mass spectrometry (UHPLC-HRMS))
33068521
888
Nervonic acid (C24:1)
female gamete generation
not
oocyte development
GO:0048599
Homo sapiens
Metabolic profiling of human follicular fluid identifies potential biomarkers of oocyte developmental competence
23886995
889
N-Formyl-L-methionine
female gamete generation
Not
oogenesis
GO:0048477
Mus musculus
Not significantly changed metabolites during meiotic maturation (GV, GVBD, MII) (Metabolomics data: ultra-high-performance liquid chromatography-tandem high-resolution mass spectrometry (UHPLC-HRMS))
33068521
890
Nicotinamide
female gamete generation
related
oogenesis
GO:0048477
Mus musculus
Significantly changed metabolites during meiotic maturation (GV, GVBD, MII) (Metabolomics data: ultra-high-performance liquid chromatography-tandem high-resolution mass spectrometry (UHPLC-HRMS))
33068521
891
Nivalenol
female gamete generation
affect
oocyte maturation
GO:0001556
Mus musculus
nivalenol affects oocyte maturation
35016910
892
Nivalenol
female gamete generation
decrease
oocyte maturation
GO:0001556
Mus musculus
[nivalenol affects oocyte maturation] which results in decreased spindle assembly involved in female meiosis
35016910
893
Nivalenol
female gamete generation
decrease
oocyte maturation
GO:0001556
Mus musculus
[nivalenol affects oocyte maturation] which results in decreased chromosome localization
35016910
894
Nivalenol
female gamete generation
affect
oogenesis
GO:0009790
Mus musculus
Exposure to nivalenol declines mouse oocyte quality via inducing oxidative stress-related apoptosis and DNA damage?
Exposure to nivalenol declines mouse oocyte quality via inducing oxidative stress-related apoptosis and DNA damage?
895
nonylphenol
female gamete generation
affect
oocyte development
GO:0048599
Mus musculus
Nonylphenol affects oocyte development
32645552
896
Norvaline
female gamete generation
related
oogenesis
GO:0048477
Mus musculus
Significantly changed metabolites during meiotic maturation (GV, GVBD, MII) (Metabolomics data: ultra-high-performance liquid chromatography-tandem high-resolution mass spectrometry (UHPLC-HRMS))
33068521
897
Octadecanamide
female gamete generation
related
oogenesis
GO:0048477
Mus musculus
Significantly changed metabolites during meiotic maturation (GV, GVBD, MII) (Metabolomics data: ultra-high-performance liquid chromatography-tandem high-resolution mass spectrometry (UHPLC-HRMS))
33068521
898
Okadaic acid
female gamete generation
affect
oocyte aneuploidy
N/A
Mus musculus
Okadaic acid, an inhibitor of protein phosphatase 1 and 2A, induces premature separation of sister chromatids during meiosis I and aneuploidy in mouse oocytes in vitro.
14516070
899
Oleic acid (C18:1n9c)
female gamete generation
not
oocyte development
GO:0048599
Homo sapiens
Metabolic profiling of human follicular fluid identifies potential biomarkers of oocyte developmental competence
23886995
900
Orotic acid
female gamete generation
Not
oogenesis
GO:0048477
Mus musculus
Not significantly changed metabolites during meiotic maturation (GV, GVBD, MII) (Metabolomics data: ultra-high-performance liquid chromatography-tandem high-resolution mass spectrometry (UHPLC-HRMS))
33068521
For any questions on the database, please send E-mail to caoyuedi@sjtu.edu.cn.
