Chemicals with Transgenerational Effects on Disease or Function
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entries
No.
Chemical Name
GO Biological Process
Effect
Specific BP
GO
Species
Description
PMID
481
S-Adenosyl-methionine
embryo development
related
embryo development
GO:0009790
Mus musculus
Significantly changed metabolites in the two-cell-like cell (2CLC) compared with ES cells (ESCs) samples (Metabolomics data: liquid chromatography
34428399
482
S-Adenosyl-methionine
embryo development
related
embryo development
GO:0009790
Mus musculus
Higher in the blastocyst-stage embryos compared with two-cell embryos (Metabolomics data: liquid chromatography
34650276
483
Salicylic Acid
embryo development
affect
regulation of gastrulation
GO:0010470
Mus musculus
Salicylic Acid affects regulation of gastrulation
28184906
484
SB431542
embryo development
affect
ESC differentiation
N/A
Homo sapiens
The synergistic action of two inhibitors of SMAD signaling, Noggin and SB431542, is sufficient to induce rapid and complete neural conversion of >80% of hES cells under adherent culture conditions.
19252484, 19896224
485
SDMA-ADMA
embryo development
related
embryo development
GO:0009790
Mus musculus
Significantly changed metabolites in the two-cell-like cell (2CLC) compared with ES cells (ESCs) samples (Metabolomics data: liquid chromatography
34428399
486
SDMA-ADMA
embryo development
related
embryo development
GO:0009790
Mus musculus
Higher in the blastocyst-stage embryos compared with two-cell embryos (Metabolomics data: liquid chromatography
34650276
487
Sedoheptulose 7-phosphate
embryo development
related
embryo development
GO:0009790
Mus musculus
Metabolite dynamics during mouse embryo development (Zygote, 2-cell, 4-cell, 8-cell, Morula, Blastocyst) (Metabolomics data: ultra-high-performance liquid chromatography coupled with hybrid quadrupole time-of-flight mass spectrometry (UHPLC
36167681
488
Serine
embryo development
related
embryo development
GO:0009790
Mus musculus
Metabolite dynamics during mouse embryo development (Zygote, 2-cell, 4-cell, 8-cell, Morula, Blastocyst) (Metabolomics data: ultra-high-performance liquid chromatography coupled with hybrid quadrupole time-of-flight mass spectrometry (UHPLC
36167681
489
Serotonin?
embryo development
affect
heart morphogenesis
GO:0003007
Mus musculus
Serotonin?(5-HT) may play a role in cardiac morphogenesis during endocardial cushion formation.
8367830, 3209688
490
Sertraline
embryo development
affect
embryo development
GO:0009790
Mus musculus
Exposure of mouse embryos in whole embryo culture to sertraline caused craniofacial malformations.
1412065
491
Silver nanoparticles (AgNPs)
embryo development
affect
embryo development
GO:0009790
Mus musculus
Co-treatment with noncytotoxic concentrations of AgNPs (10
35782646
492
Sirtinol
embryo development
decrease
embryonic limb morphogenesis
GO:0030326
Mus musculus
sirtinol results in decreased embryonic limb morphogenesis
26251326
493
5'-Methylthioadenosine
embryo development
related
embryo development
GO:0009790
Mus musculus
Significantly changed metabolites in the two-cell-like cell (2CLC) compared with ES cells (ESCs) samples (Metabolomics data: liquid chromatography
34428399
494
5'-Methylthioadenosine
embryo development
related
embryo development
GO:0009790
Mus musculus
Higher in the blastocyst-stage embryos compared with two-cell embryos (Metabolomics data: liquid chromatography
34650276
495
S-Methylmethionine
embryo development
related
embryo development
GO:0009790
Mus musculus
Metabolite dynamics during mouse embryo development (Zygote, 2-cell, 4-cell, 8-cell, Morula, Blastocyst) (Metabolomics data: ultra-high-performance liquid chromatography coupled with hybrid quadrupole time-of-flight mass spectrometry (UHPLC
36167681
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