Chemicals with Transgenerational Effects on Disease or Function

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No. Chemical Name GO Biological Process Effect Specific BP GO Species Description PMID
162-deoxy-glucoseembryo developmentrelatedembryo developmentGO:0009790Mus musculusMetabolite dynamics during mouse embryo development (Zygote, 2-cell, 4-cell, 8-cell, Morula, Blastocyst) (Metabolomics data: ultra-high-performance liquid chromatography coupled with hybrid quadrupole time-of-flight mass spectrometry (UHPLC36167681
172-deoxyinosineembryo developmentrelatedembryo developmentGO:0009790Mus musculusMetabolite dynamics during mouse embryo development (Zygote, 2-cell, 4-cell, 8-cell, Morula, Blastocyst) (Metabolomics data: ultra-high-performance liquid chromatography coupled with hybrid quadrupole time-of-flight mass spectrometry (UHPLC36167681
182-Deoxy-ribose-5-phosphateembryo developmentrelatedembryo developmentGO:0009790Mus musculusMetabolite dynamics during mouse embryo development (Zygote, 2-cell, 4-cell, 8-cell, Morula, Blastocyst) (Metabolomics data: ultra-high-performance liquid chromatography coupled with hybrid quadrupole time-of-flight mass spectrometry (UHPLC36167681
192-Hydroxyglutarateembryo developmentrelatedembryo developmentGO:0009790Mus musculusHigher in the blastocyst-stage embryos compared with two-cell embryos (Metabolomics data: liquid chromatography34650276
202-Hydroxyisocaproateembryo developmentrelatedembryo developmentGO:0009790Mus musculusHigher in the blastocyst-stage embryos compared with two-cell embryos (Metabolomics data: liquid chromatography34650276
213,4-dihydropyrimido[4,5-d]pyrimidinesembryo developmentaffectESC differentiationN/AMus musculusA class of 3,4-dihydropyrimido[4,5-d]pyrimidines was characterized that maintain the undifferentiated phenotype of mES cells in a dose-dependent manner17088537
223-Methylhistidineembryo developmentrelatedembryo developmentGO:0009790Mus musculusHigher in the blastocyst-stage embryos compared with two-cell embryos (Metabolomics data: liquid chromatography34650276
233-Phenyllactateembryo developmentrelatedembryo developmentGO:0009790Mus musculusHigher in the blastocyst-stage embryos compared with two-cell embryos (Metabolomics data: liquid chromatography34650276
243-Phenyllactic acidembryo developmentrelatedembryo developmentGO:0009790Mus musculusSignificantly changed metabolites in the two-cell-like cell (2CLC) compared with ES cells (ESCs) samples (Metabolomics data: liquid chromatography34428399
25SB431542embryo developmentincreaseneural plate developmentGO:0001840Homo sapiens[[Chir 99021 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with Tretinoin] affects cell differentiation] which results in increased neural plate development31711903
264-Hydroxybenzoateembryo developmentrelatedembryo developmentGO:0009790Mus musculusHigher in the blastocyst-stage embryos compared with two-cell embryos (Metabolomics data: liquid chromatography34650276
274-Hydroxybenzoic acidembryo developmentrelatedembryo developmentGO:0009790Mus musculusSignificantly changed metabolites in the two-cell-like cell (2CLC) compared with ES cells (ESCs) samples (Metabolomics data: liquid chromatography34428399
285-aza-2embryo developmentincreaseembryo developmentGO:0009790Homo sapiensthe cardiomyocyte differentiation of human ES cells is enhanced by treatment of 5-aza-217979183?
295-Azacytidineembryo developmentincreaseembryo developmentGO:0009790Homo sapiens It is a potent inducer of cardiomyogenic differentiation in bone marrow-derived mesenchymal stem cells 15023550, 17979183
305-Azacytidineembryo developmentincreaseembryo developmentGO:0009790Homo sapiens?It is a potent inducer of cardiomyogenic differentiation in both embryonic cells.17979183?

Showing 16 to 30 of 1481 entries

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Copyright © Haifeng Chen Lab, Shanghai Jiao Tong University.