Proteins with Transgenerational Effects on Disease or Function

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No. Entry Entry Name Protein Names Gene Names Organism GO Biological Process Structure PDB ID for Docking Interaction Molecules
4411Q96MU7YTDC1_HUMANYTH domain-containing protein 1 (Splicing factor YT521) (YT521-B)YTHDC1 KIAA1966 YT521Homo sapiens (Human)Female gamete generation; Male gamete generation; embryo development6YKZLysophosphatidylcholine
4412Q9NPJ1MKKS_HUMANMolecular chaperone MKKS (Bardet-Biedl syndrome 6 protein) (McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin)MKKS BBS6Homo sapiens (Human)Male gamete generationQ9NPJ1Lysophosphatidylcholine
4413Q9NXK6PAQR5_HUMANMembrane progestin receptor gamma (mPR gamma) (Membrane progesterone P4 receptor gamma) (Membrane progesterone receptor gamma) (Progesterone and adipoQ receptor family member 5) (Progestin and adipoQ receptor family member 5) (Progestin and adipoQ receptor family member V)PAQR5 MPRGHomo sapiens (Human)Female gamete generationQ9NXK6Lysophosphatidylcholine
4414Q9UHI6DDX20_HUMANProbable ATP-dependent RNA helicase DDX20 (EC 3.6.1.15) (EC 3.6.4.13) (Component of gems 3) (DEAD box protein 20) (DEAD box protein DP 103) (Gemin-3)DDX20 DP103 GEMIN3Homo sapiens (Human)Female gamete generation2OXCLysophosphatidylcholine
4415Q96KQ7EHMT2_HUMANHistone-lysine N-methyltransferase EHMT2 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Lysine N-methyltransferase 1C) (Protein G9a)EHMT2 BAT8 C6orf30 G9A KMT1C NG36Homo sapiens (Human)Female gamete generation; Male gamete generation; embryo development7X73Lysophosphatidylcholine
4416Q12768WASC5_HUMANWASH complex subunit 5 (Strumpellin) (WASH complex subunit strumpellin)WASHC5 KIAA0196Homo sapiens (Human)Female gamete generationQ12768Lysophosphatidylcholine
4417O00238BMR1B_HUMANBone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (CD antigen CDw293)BMPR1BHomo sapiens (Human)Female gamete generation3MDYLysophosphatidylcholine
4418P40692MLH1_HUMANDNA mismatch repair protein Mlh1 (MutL protein homolog 1)MLH1 COCA2Homo sapiens (Human)Female gamete generationP40692Lysophosphatidylcholine
4419P17813EGLN_HUMANEndoglin (CD antigen CD105)ENG ENDHomo sapiens (Human)embryo development5I04Lysophosphatidylcholine
4420P42338PK3CB_HUMANPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (PI3-kinase subunit beta) (PI3K-beta) (PI3Kbeta) (PtdIns-3-kinase subunit beta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta) (PtdIns-3-kinase subunit p110-beta) (p110beta) (Serine/threonine protein kinase PIK3CB) (EC 2.7.11.1)PIK3CB PIK3C1Homo sapiens (Human)Embryo developmentP42338Lysophosphatidylcholine
4421Q16881TRXR1_HUMANThioredoxin reductase 1, cytoplasmic (TR) (EC 1.8.1.9) (Gene associated with retinoic and interferon-induced mortality 12 protein) (GRIM-12) (Gene associated with retinoic and IFN-induced mortality 12 protein) (KM-102-derived reductase-like factor) (Peroxidase TXNRD1) (EC 1.11.1.2) (Thioredoxin reductase TR1)TXNRD1 GRIM12 KDRFHomo sapiens (Human)embryo development3QFBLysophosphatidylcholine
4422Q86WK9PAQR7_HUMANMembrane progestin receptor alpha (mPR alpha) (Membrane progesterone P4 receptor alpha) (Membrane progesterone receptor alpha) (Progesterone and adipoQ receptor family member 7) (Progestin and adipoQ receptor family member 7) (Progestin and adipoQ receptor family member VII)PAQR7 MRPAHomo sapiens (Human)Female gamete generationQ86WK9Lysophosphatidylcholine
4423P11388TOP2A_HUMANDNA topoisomerase 2-alpha (EC 5.6.2.2) (DNA topoisomerase II, alpha isozyme)TOP2A TOP2Homo sapiens (Human)embryo development1ZXMLysophosphatidylcholine
4424O76074PDE5A_HUMANcGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35) (cGMP-binding cGMP-specific phosphodiesterase) (CGB-PDE)PDE5A PDE5Homo sapiens (Human)Female gamete generationO76074Lysophosphatidylcholine
4425Q03113GNA12_HUMANGuanine nucleotide-binding protein subunit alpha-12 (G alpha-12) (G-protein subunit alpha-12)GNA12Homo sapiens (Human)Embryo developmentQ03113Lysophosphatidylcholine

Showing 4411 to 4425 of 5032 entries

For any questions on the database, please send E-mail to caoyuedi@sjtu.edu.cn.

Copyright © Haifeng Chen Lab, Shanghai Jiao Tong University.