Chemicals with Transgenerational Effects on Disease or Function

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No. Chemical Name GO Biological Process Effect Specific BP GO Species Description PMID
1411Sodium nitroprussidemale gamete generationdecreasepositive regulation of flagellated sperm motility involved in capacitationGO:0060474Mus musculussodium nitroprusside inhibited sperm motility and motion kinematics in a dose-dependent manner by significantly enhancing intracellular iron and reactive oxygen species (ROS), and decreasing Ca2+, and adenosine triphosphate levels in spermatozoa.25180787
1412sodium sulfidemale gamete generationaffectspermatogenesisGO:0007283Mus musculusFatty Acids, Omega-3 inhibits the reaction [[Hydrogen Sulfide results in increased abundance of sodium sulfide] which affects spermatogenesis]33068716
1413sodium sulfidemale gamete generationdecreasespermatogenesisGO:0007283Mus musculus[Hydrogen Sulfide results in increased abundance of sodium sulfide] which results in decreased spermatogenesis33068716
1414Stigmasterolmale gamete generationdecreasespermatid developmentGO:0007286Mus musculus[bisphenol A co-treated with Stigmasterol] results in decreased spermatid development30245210
1415Stigmasterolmale gamete generationdecreasespermatid developmentGO:0007286Mus musculusNR1H4 gene mutant form inhibits the reaction [[bisphenol A co-treated with Stigmasterol] results in decreased spermatid development]30245210
1416Stigmasterolmale gamete generationdecreasespermatocyte divisionGO:0048137Mus musculus[bisphenol A co-treated with Stigmasterol] results in decreased spermatocyte division30245210
1417Stigmasterolmale gamete generationdecreasespermatocyte divisionGO:0048137Mus musculusNR1H4 gene mutant form inhibits the reaction [[bisphenol A co-treated with Stigmasterol] results in decreased spermatocyte division]30245210
1418Sucrosemale gamete generationaffectpositive regulation of flagellated sperm motility involved in capacitationGO:0060474Mus musculusSucrose can be used as effectively as raffinose for mouse sperm cryopreservation.30036078
1419Sulfasalazinemale gamete generationdecreasespermatogenesisGO:0007283Mus musculusSulfasalazine results in decreased spermatogenesis28421826
1420Sulfasalazinemale gamete generationdecreasespermatogenesisGO:0007283Mus musculusSulfasalazine inhibits the reaction [Dextran Sulfate results in decreased spermatogenesis]28421826
1421Sulfogalactosylglycerolipidmale gamete generationaffectspermatogenesisGO:0007283Mus musculusSperm sulfogalactosylglycerolipid (SGG) is involves in direct binding to the zona pellucida (ZP).10859254
1422Sulfogalactosylglycerolipidmale gamete generationrelatespermatogenesisGO:0007283Mus musculusSulfogalactosylglycerolipid (SGG) is higher in the group of sperm with higher fertilization capacity.34445473, 15525814
1423Sulfogalactosylglycerolipidmale gamete generationaffectspermatogenesisGO:0007283Homo sapiensSulfogalactosylglycerolipid (SGG) is involved in human gamete interaction.11746968
1424Sulforaphanemale gamete generationaffectspermatogenesisGO:0007283Mus musculusSulforaphane inhibits the reaction [Busulfan affects spermatogenesis]32416107
1425Sulfur Dioxidemale gamete generationdecreasespermatogenesisGO:0007283Mus musculusSulfur Dioxide results in decreased spermatogenesis30195209

Showing 1411 to 1425 of 1481 entries

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Copyright © Haifeng Chen Lab, Shanghai Jiao Tong University.