Chemicals with Transgenerational Effects on Disease or Function

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No. Chemical Name GO Biological Process Effect Specific BP GO Species Description PMID
526Strontium chlorideembryo developmentincreaseembryo developmentGO:0009790Mus musculusSix-hour treatment with 10 mmol/L strontium chloride (SrCl2) in Ca2+ alone or in combination with cytochalasin B can well activate nuclear transfer embryos in mice.23297500
527Succinateembryo developmentrelatedembryo developmentGO:0009790Mus musculusHigher in the blastocyst-stage embryos compared with two-cell embryos (Metabolomics data: liquid chromatography34650276
528Succinylcholineembryo developmentrelatedembryo developmentGO:0009790Mus musculusMetabolite dynamics during mouse embryo development (Zygote, 2-cell, 4-cell, 8-cell, Morula, Blastocyst) (Metabolomics data: ultra-high-performance liquid chromatography coupled with hybrid quadrupole time-of-flight mass spectrometry (UHPLC36167681
529Taurineembryo developmentnotembryo developmentGO:0009790Mus musculusBeta-alanine but not taurine can function as an organic osmolyte in preimplantation mouse embryos cultured from fertilized eggs12950102
530Tauroursodeoxycholic acidembryo developmentincreaseembryo developmentGO:0009790Mus musculusTauroursodeoxycholic acid (TUDCA) improved the developmental competence of mouse embryos by attenuating endoplasmic reticulum (ER) stress-induced apoptosis during preimplantation development31802346
531Tauroursodeoxycholic acidembryo developmentincreaseembryo developmentGO:0009790Mus musculusTauroursodeoxycholic acid improves the implantation and live-birth rates of mouse embryos.26051458, 31802346
532Taxolembryo developmentaffectembryo developmentGO:0009790Mus musculusTaxol-induced meiotic maturation delay, spindle defects, and aneuploidy in mouse oocytes and zygotes.10029682
533Tetrachlorodibenzodioxinembryo developmentdecreaseprostatic bud formationGO:0060513Mus musculusTetrachlorodibenzodioxin results in decreased prostatic bud formation24928892
534Thalidomideembryo developmentnotembryo developmentGO:0009790Homo sapiensThalidomide did not reduce viability in any of the concentrations tested in human induced pluripotent stem cell (hiPSC)-derived embryoid bodies (EB)32700165
535Thiaclopridembryo developmentdecreaseblastocyst developmentGO:0001824Mus musculusthiacloprid results in decreased blastocyst development29061322
536Thiaclopridembryo developmentdecreaseembryonic cleavageGO:0040016Mus musculusthiacloprid results in decreased embryonic cleavage29061322
537Thiamethoxamembryo developmentdecreaseblastocyst developmentGO:0001824Mus musculusThiamethoxam results in decreased blastocyst development29061322
538Thiamethoxamembryo developmentdecreaseembryonic cleavageGO:0040016Mus musculusThiamethoxam results in decreased embryonic cleavage29061322
539Thiamineembryo developmentrelatedembryo developmentGO:0009790Mus musculusHigher in the blastocyst-stage embryos compared with two-cell embryos (Metabolomics data: liquid chromatography34650276
540Thiamine pyrophosphateembryo developmentrelatedembryo developmentGO:0009790Mus musculusSignificantly changed metabolites in the two-cell-like cell (2CLC) compared with ES cells (ESCs) samples (Metabolomics data: liquid chromatography34428399

Showing 526 to 540 of 1481 entries

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Copyright © Haifeng Chen Lab, Shanghai Jiao Tong University.