Proteins with Transgenerational Effects on Disease or Function

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No. Entry Entry Name Protein Names Gene Names Organism GO Biological Process Structure PDB ID for Docking Interaction Molecules
526P27782LEF1_MOUSELymphoid enhancer-binding factor 1 (LEF-1)Lef1 Lef-1Mus musculus (Mouse)Embryo development3OUXCaffeine
527Q8BYB9PGLT1_MOUSEProtein O-glucosyltransferase 1 (EC 2.4.1.376) (CAP10-like 46 kDa protein) (KTEL motif-containing protein 1) (O-glucosyltransferase Rumi homolog) (Rumi) (Protein O-xylosyltransferase POGLUT1) (EC 2.4.2.63) (Wing-shaped neural plate protein) (Wsnp)Poglut1 Clp46 Ktelc1Mus musculus (Mouse)embryo developmentQ8BYB9Caffeine
528P27037AVR2A_HUMANActivin receptor type-2A (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) (ACTRIIA)ACVR2A ACVR2Homo sapiens (Human)Male gamete generation3SOCCaffeine
529O95714HERC2_HUMANE3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2)HERC2Homo sapiens (Human)Male gamete generation3KCICaffeine
530Q9NPJ1MKKS_HUMANMolecular chaperone MKKS (Bardet-Biedl syndrome 6 protein) (McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin)MKKS BBS6Homo sapiens (Human)Male gamete generationQ9NPJ1Caffeine
531P41586PACR_HUMANPituitary adenylate cyclase-activating polypeptide type I receptor (PACAP type I receptor) (PACAP-R-1) (PACAP-R1)ADCYAP1R1Homo sapiens (Human)Male gamete generation3N94Caffeine
532P68040RACK1_MOUSEReceptor of activated protein C kinase 1 (12-3) (Guanine nucleotide-binding protein subunit beta-2-like 1) (Receptor for activated C kinase) (Receptor of activated protein kinase C 1) (p205) [Cleaved into: Receptor of activated protein C kinase 1, N-terminally processed (Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed)]Rack1 Gnb2-rs1 Gnb2l1Mus musculus (Mouse)Embryo development7CPUp68040Caffeine
533Q9NY65TBA8_HUMANTubulin alpha-8 chain (EC 3.6.5.-) (Alpha-tubulin 8) (Tubulin alpha chain-like 2) [Cleaved into: Dephenylalaninated tubulin alpha-8 chain]TUBA8 TUBAL2Homo sapiens (Human)Male gamete generationQ9NY65Caffeine
534Q9Z2N8ACL6A_MOUSEActin-like protein 6A (53 kDa BRG1-associated factor A) (Actin-related protein Baf53a) (BRG1-associated factor 53A) (BAF53A)Actl6a Actl6 Baf53aMus musculus (Mouse)embryo developmentQ9Z2N8Caffeine
535P78396CCNA1_HUMANCyclin-A1CCNA1Homo sapiens (Human)Male gamete generationP78396Caffeine
536P35846FOLR1_MOUSEFolate receptor alpha (FR-alpha) (Folate receptor 1) (Folate-binding protein 1)Folr1 Fbp1 Folbp1Mus musculus (Mouse)FertilizationP35846Caffeine
537Q8VHI3OFUT2_MOUSEGDP-fucose protein O-fucosyltransferase 2 (EC 2.4.1.221) (Peptide-O-fucosyltransferase 2) (O-FucT-2)Pofut2Mus musculus (Mouse)embryo developmentQ8VHI3Caffeine
538P97478COQ7_MOUSE5-demethoxyubiquinone hydroxylase, mitochondrial (DMQ hydroxylase) (EC 1.14.99.60) (Timing protein clk-1 homolog) (Ubiquinone biosynthesis monooxygenase COQ7)Coq7Mus musculus (Mouse)embryo developmentP97478Caffeine
539Q96KQ7EHMT2_HUMANHistone-lysine N-methyltransferase EHMT2 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Lysine N-methyltransferase 1C) (Protein G9a)EHMT2 BAT8 C6orf30 G9A KMT1C NG36Homo sapiens (Human)Female gamete generation; Male gamete generation; embryo development5VSCCaffeine
540P19784CSK22_HUMANCasein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)CSNK2A2 CK2A2Homo sapiens (Human)Male gamete generation6HMDCaffeine

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Copyright © Haifeng Chen Lab, Shanghai Jiao Tong University.