Proteins with Transgenerational Effects on Disease or Function

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No. Entry Entry Name Protein Names Gene Names Organism GO Biological Process Structure PDB ID for Docking Interaction Molecules
496Q61456CCNA1_MOUSECyclin-A1Ccna1Mus musculus (Mouse)Male gamete generationQ61456Busulfan
497Q8CG03PDE5A_MOUSEcGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35) (cGMP-binding cGMP-specific phosphodiesterase) (CGB-PDE)Pde5a Pde5Mus musculus (Mouse)Female gamete generation2K31Busulfan
498P05480SRC_MOUSEProto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)SrcMus musculus (Mouse)Female gamete generation6F3FBusulfan
499P0DP43CTSRE_MOUSECation channel sperm-associated auxiliary subunit epsilon (CatSper-epsilon) (CatSperepsilon) (C1orf101-like protein)Catspere Catspere1 Gm7068Mus musculus (Mouse)Male gamete generation7EEBP0DP43Busulfan
500P70296PEBP1_MOUSEPhosphatidylethanolamine-binding protein 1 (PEBP-1) (HCNPpp) [Cleaved into: Hippocampal cholinergic neurostimulating peptide (HCNP)]Pebp1 Pbp PebpMus musculus (Mouse)Male gamete generation6ENSBusulfan
501Q8ND76CCNY_HUMANCyclin-Y (Cyc-Y) (Cyclin box protein 1) (Cyclin fold protein 1) (cyclin-X)CCNY C10orf9 CBCP1 CFP1Homo sapiens (Human)Male gamete generationQ8ND76Busulfan
502Q96EB6SIR1_HUMANNAD-dependent protein deacetylase sirtuin-1 (hSIRT1) (EC 2.3.1.286) (NAD-dependent protein deacylase sirtuin-1) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 1) (SIR2-like protein 1) (hSIR2) [Cleaved into: SirtT1 75 kDa fragment (75SirT1)]SIRT1 SIR2L1Homo sapiens (Human)Male gamete generation4KXQBusulfan
503Q3UA06PCH2_MOUSEPachytene checkpoint protein 2 homolog (Thyroid hormone receptor interactor 13) (Thyroid receptor-interacting protein 13) (TR-interacting protein 13) (TRIP-13)Trip13 Pch2Mus musculus (Mouse)Female gamete generationQ3UA06Busulfan
504P05132KAPCA_MOUSEcAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)Prkaca PkacaMus musculus (Mouse)Male gamete generation; Embryo development7V0GBusulfan
505Q8CJ27ASPM_MOUSEAbnormal spindle-like microcephaly-associated protein homolog (Calmodulin-binding protein Sha1) (Calmodulin-binding protein 1) (Spindle and hydroxyurea checkpoint abnormal protein)Aspm Calmbp1 Sha1Mus musculus (Mouse)Female gamete generation5LB7Busulfan
506Q64374RGN_MOUSERegucalcin (RC) (Gluconolactonase) (GNL) (EC 3.1.1.17) (Senescence marker protein 30) (SMP-30)Rgn Smp30Mus musculus (Mouse)Male gamete generation4GN8Busulfan
507P10761ZP3_MOUSEZona pellucida sperm-binding protein 3 (Sperm receptor) (Zona pellucida glycoprotein 3) (Zp-3) (Zona pellucida protein C) [Cleaved into: Processed zona pellucida sperm-binding protein 3]Zp3 Zp-3 ZpcMus musculus (Mouse)Female gamete generation; Fertilization5OSQBusulfan
508Q9DCU0PAQR5_MOUSEMembrane progestin receptor gamma (mPR gamma) (Membrane progesterone P4 receptor gamma) (Membrane progesterone receptor gamma) (Progesterone and adipoQ receptor family member 5) (Progestin and adipoQ receptor family member 5) (Progestin and adipoQ receptor family member V)Paqr5 MprgMus musculus (Mouse)Female gamete generationQ9DCU0Busulfan
509P78396CCNA1_HUMANCyclin-A1CCNA1Homo sapiens (Human)Male gamete generationP78396Busulfan
510P41586PACR_HUMANPituitary adenylate cyclase-activating polypeptide type I receptor (PACAP type I receptor) (PACAP-R-1) (PACAP-R1)ADCYAP1R1Homo sapiens (Human)Male gamete generation3N94Busulfan

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Copyright © Haifeng Chen Lab, Shanghai Jiao Tong University.