Proteins with Transgenerational Effects on Disease or Function

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entries
No. Entry Entry Name Protein Names Gene Names Organism GO Biological Process Structure PDB ID for Docking Interaction Molecules
3076Q64374RGN_MOUSERegucalcin (RC) (Gluconolactonase) (GNL) (EC 3.1.1.17) (Senescence marker protein 30) (SMP-30)Rgn Smp30Mus musculus (Mouse)Male gamete generation4GN8perfluorooctane sulfonic acid
3077P37059DHB2_HUMAN17-beta-hydroxysteroid dehydrogenase type 2 (17-beta-HSD 2) (20 alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (E2DH) (Estradiol 17-beta-dehydrogenase 2) (EC 1.1.1.62) (Microsomal 17-beta-hydroxysteroid dehydrogenase) (Short chain dehydrogenase/reductase family 9C member 2) (Testosterone 17-beta-dehydrogenase) (EC 1.1.1.239)HSD17B2 EDH17B2 SDR9C2Homo sapiens (Human)Embryo developmentP37059perfluoroundecanoic acid
3078Q15475SIX1_HUMANHomeobox protein SIX1 (Sine oculis homeobox homolog 1)SIX1Homo sapiens (Human)embryo development4EGCperfluoroundecanoic acid
3079P06493CDK1_HUMANCyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)CDK1 CDC2 CDC28A CDKN1 P34CDC2Homo sapiens (Human)Fertilization6GU2perfluoroundecanoic acid
3080Q15562TEAD2_HUMANTranscriptional enhancer factor TEF-4 (TEA domain family member 2) (TEAD-2)TEAD2 TEF4Homo sapiens (Human)embryo development3L15perfluoroundecanoic acid
3081Q13683ITA7_HUMANIntegrin alpha-7 [Cleaved into: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; Integrin alpha-7 70 kDa form]ITGA7 UNQ406/PRO768Homo sapiens (Human)Embryo developmentQ13683perfluoroundecanoic acid
3082P53708ITA8_HUMANIntegrin alpha-8 [Cleaved into: Integrin alpha-8 heavy chain; Integrin alpha-8 light chain]ITGA8Homo sapiens (Human)Embryo developmentP53708perfluoroundecanoic acid
3083Q14651PLSI_HUMANPlastin-1 (Intestine-specific plastin) (I-plastin)PLS1Homo sapiens (Human)Embryo developmentQ14651perfluoroundecanoic acid
3084Q7Z494NPHP3_HUMANNephrocystin-3NPHP3 KIAA2000Homo sapiens (Human)embryo development5L7Kperfluoroundecanoic acid
3085P10826RARB_HUMANRetinoic acid receptor beta (RAR-beta) (HBV-activated protein) (Nuclear receptor subfamily 1 group B member 2) (RAR-epsilon)RARB HAP NR1B2Homo sapiens (Human)embryo development4DM6perfluoroundecanoic acid
3086Q8IZL9CDK20_HUMANCyclin-dependent kinase 20 (EC 2.7.11.22) (CDK-activating kinase p42) (CAK-kinase p42) (Cell cycle-related kinase) (Cell division protein kinase 20) (Cyclin-dependent protein kinase H) (Cyclin-kinase-activating kinase p42)CDK20 CCRK CDCHHomo sapiens (Human)Embryo developmentQ8IZL9perfluoroundecanoic acid
3087O88879APAF_MOUSEApoptotic protease-activating factor 1 (APAF-1)Apaf1Mus musculus (Mouse)Embryo development3SFZBexarotene
3088P35846FOLR1_MOUSEFolate receptor alpha (FR-alpha) (Folate receptor 1) (Folate-binding protein 1)Folr1 Fbp1 Folbp1Mus musculus (Mouse)FertilizationP35846Bexarotene
3089Q925J9MED1_MOUSEMediator of RNA polymerase II transcription subunit 1 (Mediator complex subunit 1) (Peroxisome proliferator-activated receptor-binding protein) (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TR-interacting protein 2) (TRIP-2)Med1 Crsp210 Drip205 Pbp Pparbp Trap220 Trip2Mus musculus (Mouse)Embryo development1XDKBexarotene
3090P21279GNAQ_MOUSEGuanine nucleotide-binding protein G(q) subunit alpha (Guanine nucleotide-binding protein alpha-q)GnaqMus musculus (Mouse)Embryo development7SQ2Bexarotene

For any questions on the database, please send E-mail to caoyuedi@sjtu.edu.cn.

Copyright © Haifeng Chen Lab, Shanghai Jiao Tong University.