Proteins with Transgenerational Effects on Disease or Function

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No. Entry Entry Name Protein Names Gene Names Organism GO Biological Process Structure PDB ID for Docking Interaction Molecules
271Q60857SC6A4_MOUSESodium-dependent serotonin transporter (SERT) (5HT transporter) (5HTT) (Solute carrier family 6 member 4)Slc6a4 Htt SertMus musculus (Mouse)Male gamete generationQ60857Melatonin
272P21956MFGM_MOUSELactadherin (MFGM) (Milk fat globule-EGF factor 8) (MFG-E8) (SED1) (Sperm surface protein SP47) (MP47)Mfge8Mus musculus (Mouse)Fertilization2L9LMelatonin
273P18911RARG_MOUSERetinoic acid receptor gamma (RAR-gamma) (Nuclear receptor subfamily 1 group B member 3)Rarg Nr1b3Mus musculus (Mouse)embryo developmentP18911Melatonin
274Q14432PDE3A_HUMANcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A) (cGMP-inhibited cAMP phosphodiesterase) (cGI-PDE)PDE3AHomo sapiens (Human)Female gamete generation7L27Melatonin
275P08910ABHD2_HUMANMonoacylglycerol lipase ABHD2 (EC 3.1.1.23) (2-arachidonoylglycerol hydrolase) (Abhydrolase domain-containing protein 2) (Acetylesterase) (EC 3.1.1.6) (Lung alpha/beta hydrolase 2) (Progesterone-sensitive lipase) (EC 3.1.1.79) (Protein PHPS1-2)ABHD2 LABH2Homo sapiens (Human)Male gamete generationP08910Melatonin
276P07686HEXB_HUMANBeta-hexosaminidase subunit beta (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit beta) (Hexosaminidase subunit B) (Cervical cancer proto-oncogene 7 protein) (HCC-7) (N-acetyl-beta-glucosaminidase subunit beta) [Cleaved into: Beta-hexosaminidase subunit beta chain B; Beta-hexosaminidase subunit beta chain A]HEXB HCC7Homo sapiens (Human)Female gamete generation; Fertilization1NOWMelatonin
277P37059DHB2_HUMAN17-beta-hydroxysteroid dehydrogenase type 2 (17-beta-HSD 2) (20 alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (E2DH) (Estradiol 17-beta-dehydrogenase 2) (EC 1.1.1.62) (Microsomal 17-beta-hydroxysteroid dehydrogenase) (Short chain dehydrogenase/reductase family 9C member 2) (Testosterone 17-beta-dehydrogenase) (EC 1.1.1.239)HSD17B2 EDH17B2 SDR9C2Homo sapiens (Human)Embryo developmentP37059Melatonin
278Q8TC94ACTL9_HUMANActin-like protein 9ACTL9 ACTL7C HSD21Homo sapiens (Human)Male gamete generationQ8TC94Melatonin
279P35846FOLR1_MOUSEFolate receptor alpha (FR-alpha) (Folate receptor 1) (Folate-binding protein 1)Folr1 Fbp1 Folbp1Mus musculus (Mouse)FertilizationP35846Melatonin
280Q9JK91MLH1_MOUSEDNA mismatch repair protein Mlh1 (MutL protein homolog 1)Mlh1Mus musculus (Mouse)Female gamete generationQ9JK91Melatonin
281Q8IZL9CDK20_HUMANCyclin-dependent kinase 20 (EC 2.7.11.22) (CDK-activating kinase p42) (CAK-kinase p42) (Cell cycle-related kinase) (Cell division protein kinase 20) (Cyclin-dependent protein kinase H) (Cyclin-kinase-activating kinase p42)CDK20 CCRK CDCHHomo sapiens (Human)Embryo developmentQ8IZL9Melatonin
282P10761ZP3_MOUSEZona pellucida sperm-binding protein 3 (Sperm receptor) (Zona pellucida glycoprotein 3) (Zp-3) (Zona pellucida protein C) [Cleaved into: Processed zona pellucida sperm-binding protein 3]Zp3 Zp-3 ZpcMus musculus (Mouse)Female gamete generation; Fertilization5OSQMelatonin
283P19091ANDR_MOUSEAndrogen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)Ar Nr3c4Mus musculus (Mouse)Male gamete generation; Embryo development2QPYMelatonin
284Q8CG03PDE5A_MOUSEcGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35) (cGMP-binding cGMP-specific phosphodiesterase) (CGB-PDE)Pde5a Pde5Mus musculus (Mouse)Female gamete generation2K31Melatonin
285Q12768WASC5_HUMANWASH complex subunit 5 (Strumpellin) (WASH complex subunit strumpellin)WASHC5 KIAA0196Homo sapiens (Human)Female gamete generationQ12768Melatonin

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For any questions on the database, please send E-mail to caoyuedi@sjtu.edu.cn.

Copyright © Haifeng Chen Lab, Shanghai Jiao Tong University.