Chemicals with Transgenerational Effects on Disease or Function

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No. Chemical Name GO Biological Process Effect Specific BP GO Species Description PMID
1456Theophyllinemale gamete generationincreasepositive regulation of flagellated sperm motility involved in capacitationGO:0060474Homo sapiensPharmacological agents such as pentoxifylline, caffeine, theophylline, theobromine, and 2-deoxyadenosine, which have inhibitory effect on phosphodiesterases, have demonstrated sperm motility enhancement.33237520, 7890078, 9513850
1457tin sulfidemale gamete generationdecreasespermatogenesisGO:0007283Mus musculustin sulfide results in decreased spermatogenesis29069489
1458titanium dioxidemale gamete generationaffectspermatogenesisGO:0007283Mus musculustitanium dioxide affects spermatogenesis24241477
1459Tobacco Smoke Pollutionmale gamete generationdecreasespermatogenesisGO:0007283Homo sapiensTobacco Smoke Pollution results in decreased spermatogenesis26181561
1460Retinoic acidmale gamete generationaffectspermatogenesisGO:0007283Mus musculusTretinoin affects spermatogenesis21228214
1461Retinoic acidmale gamete generationincreasespermatogenesisGO:0007283Mus musculusTretinoin results in increased spermatogenesis21277790|6129843
1462Triclosanmale gamete generationdecreasespermatogenesisGO:0007283Homo sapiensTriclosan results in decreased spermatogenesis26901211
1463Trihalomethanesmale gamete generationdecreasespermatogenesisGO:0007283Homo sapiens[Trihalomethanes results in increased abundance of Chloroform] which results in decreased spermatogenesis31783240
1464Trihalomethanesmale gamete generationdecreasespermatogenesisGO:0007283Homo sapiens[Trihalomethanes results in increased abundance of chlorodibromomethane] which results in decreased spermatogenesis31783240
1465Triptolidemale gamete generationdecreasespermatogenesisGO:0007283Mus musculustriptolide results in decreased spermatogenesis30836114
1466Triptolidemale gamete generationdecreasespermatogenesisGO:0007283Mus musculusmitoquinone inhibits the reaction [triptolide results in decreased spermatogenesis]30836114
1467Vanadiummale gamete generationdecreasesperm capacitationGO:0048240Homo sapiensVanadium adversely affects sperm motility and capacitation status via protein kinase A activity and tyrosine phosphorylation32659260
1468Vanadiummale gamete generationdecreasepositive regulation of flagellated sperm motility involved in capacitationGO:0060474Homo sapiensVanadium adversely affects sperm motility and capacitation status via protein kinase A activity and tyrosine phosphorylation32659260
1469Vitamin Amale gamete generationdecreasespermatogenesisGO:0007283Mus musculusVitamin A results in decreased spermatogenesis30944279
1470Vitamin Dmale gamete generationaffectpositive regulation of flagellated sperm motility involved in capacitationGO:0060474Homo sapiensSeminal plasma vitamin D may be involved in regulating sperm motility,30618415

Showing 1456 to 1470 of 1481 entries

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Copyright © Haifeng Chen Lab, Shanghai Jiao Tong University.