GO with Transgenerational Effects on Disease or Function
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entries
No.
GO ID
Name
Definition
Biological Process to be more Specific
Exact Synonyms
46
GO:0060467
negative regulation of fertilization
Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).
fertilization
negative regulation of fertilization
47
GO:0060478
acrosomal vesicle exocytosis
The calcium ion regulated exocytosis which results in fusion of the acrosomal vesicle with the plasma membrane of the sperm as part of the acrosome reaction.
fertilization
acrosomal vesicle exocytosis
48
GO:2000344
positive regulation of acrosome reaction
Any process that activates or increases the frequency, rate or extent of the acrosome reaction.
fertilization
positive regulation of acrosome reaction
49
GO:0007292
female gamete generation
Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction.
Female gamete generation
female gamete generation
50
GO:0001556
oocyte maturation
A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization.
Female gamete generation
oocyte maturation
51
GO:0001544
initiation of primordial ovarian follicle growth
Increase in size of primordial follicles including proliferation and shape changes of granulosa and/or theca cells until oocyte is surrounded by one layer of cuboidal shaped granulosa cells (primary follicle).
Female gamete generation
initiation of primordial ovarian follicle growth
52
GO:0001546
preantral ovarian follicle growth
Increase in size of follicles surrounded by two or more layers of granulosa cells up to the onset of antrum formation.
Female gamete generation
preantral ovarian follicle growth
53
GO:0001550
ovarian cumulus expansion
Increase in size of the cumulus surrounding the oocyte including change in morphology due to proliferation and dispersion of cumulus cells.
Female gamete generation
ovarian cumulus expansion
54
GO:0016325
oocyte microtubule cytoskeleton organization
Formation and maintenance of a polarized microtubule array originating from a microtubule-organizing center (MTOC) in the oocyte. An example of this is found in Drosophila melanogaster.
Female gamete generation
oocyte microtubule cytoskeleton organization
55
GO:0035803
egg coat formation
Construction of an egg coat, a specialized extracellular matrix that surrounds the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development.
Female gamete generation
egg coat formation
56
GO:0043929
primary ovarian follicle growth involved in double layer follicle stage
Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle), as part of the double layer follicle stage of oogenesis.
Female gamete generation
primary ovarian follicle growth involved in double layer follicle stage
57
GO:0048160
primary follicle stage
The stage in oogenesis when a single layer of cuboidal follicle cells surrounds the oocyte. The oocyte nucleus is large.
Female gamete generation
primary follicle stage
58
GO:0048477
oogenesis
The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
Female gamete generation
oogenesis
59
GO:0048599
oocyte development
The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
Female gamete generation
oocyte development
60
GO:1900193
regulation of oocyte maturation
Any process that modulates the frequency, rate or extent of oocyte maturation.
Female gamete generation
regulation of oocyte maturation
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