Proteins with Transgenerational Effects on Disease or Function

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entries
No. Entry Entry Name Protein Names Gene Names Organism GO Biological Process Structure PDB ID for Docking Interaction Molecules
1096P78330SERB_HUMANPhosphoserine phosphatase (PSP) (PSPase) (EC 3.1.3.3) (L-3-phosphoserine phosphatase) (O-phosphoserine phosphohydrolase)PSPHHomo sapiens (Human)embryo development1NNLThalidomide
1097P06493CDK1_HUMANCyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)CDK1 CDC2 CDC28A CDKN1 P34CDC2Homo sapiens (Human)Fertilization6GU2Thalidomide
1098Q01415GALK2_HUMANN-acetylgalactosamine kinase (EC 2.7.1.157) (GalNAc kinase) (Galactokinase 2)GALK2 GK2Homo sapiens (Human)Male gamete generation2A2CTheobromine
1099Q9BXB7SPT16_HUMANSpermatogenesis-associated protein 16 (Testis development protein NYD-SP12)SPATA16Homo sapiens (Human)Male gamete generationQ9BXB7Theobromine
1100Q96EB6SIR1_HUMANNAD-dependent protein deacetylase sirtuin-1 (hSIRT1) (EC 2.3.1.286) (NAD-dependent protein deacylase sirtuin-1) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 1) (SIR2-like protein 1) (hSIR2) [Cleaved into: SirtT1 75 kDa fragment (75SirT1)]SIRT1 SIR2L1Homo sapiens (Human)Male gamete generation4KXQTheobromine
1101Q14094CCNI_HUMANCyclin-ICCNIHomo sapiens (Human)Male gamete generationQ14094Theobromine
1102Q96KQ7EHMT2_HUMANHistone-lysine N-methyltransferase EHMT2 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Lysine N-methyltransferase 1C) (Protein G9a)EHMT2 BAT8 C6orf30 G9A KMT1C NG36Homo sapiens (Human)Female gamete generation; Male gamete generation; embryo development5VSCTheobromine
1103Q9NPJ1MKKS_HUMANMolecular chaperone MKKS (Bardet-Biedl syndrome 6 protein) (McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin)MKKS BBS6Homo sapiens (Human)Male gamete generationQ9NPJ1Theobromine
1104P15259PGAM2_HUMANPhosphoglycerate mutase 2 (EC 5.4.2.11) (EC 5.4.2.4) (BPG-dependent PGAM 2) (Muscle-specific phosphoglycerate mutase) (Phosphoglycerate mutase isozyme M) (PGAM-M)PGAM2 PGAMMHomo sapiens (Human)Male gamete generationP15259Theobromine
1105O95714HERC2_HUMANE3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2)HERC2Homo sapiens (Human)Male gamete generation3KCITheobromine
1106Q8IYM1SEP12_HUMANSeptin-12SEPTIN12 SEPT12Homo sapiens (Human)Male gamete generation6MQ9Theobromine
1107P78396CCNA1_HUMANCyclin-A1CCNA1Homo sapiens (Human)Male gamete generationP78396Theobromine
1108Q14353GAMT_HUMANGuanidinoacetate N-methyltransferase (EC 2.1.1.2)GAMTHomo sapiens (Human)Male gamete generation3ORHTriclosan
1109Q00536CDK16_HUMANCyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) (PCTAIRE-motif protein kinase 1) (Serine/threonine-protein kinase PCTAIRE-1)CDK16 PCTAIRE1 PCTK1Homo sapiens (Human)Male gamete generation5G6VTriclosan
1110Q14094CCNI_HUMANCyclin-ICCNIHomo sapiens (Human)Male gamete generationQ14094Triclosan

For any questions on the database, please send E-mail to caoyuedi@sjtu.edu.cn.

Copyright © Haifeng Chen Lab, Shanghai Jiao Tong University.