Proteins with Transgenerational Effects on Disease or Function

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No. Entry Entry Name Protein Names Gene Names Organism GO Biological Process Structure PDB ID for Docking Interaction Molecules
856P07686HEXB_HUMANBeta-hexosaminidase subunit beta (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit beta) (Hexosaminidase subunit B) (Cervical cancer proto-oncogene 7 protein) (HCC-7) (N-acetyl-beta-glucosaminidase subunit beta) [Cleaved into: Beta-hexosaminidase subunit beta chain B; Beta-hexosaminidase subunit beta chain A]HEXB HCC7Homo sapiens (Human)Female gamete generation; Fertilization1NOWglyphosate
857Q8CG03PDE5A_MOUSEcGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35) (cGMP-binding cGMP-specific phosphodiesterase) (CGB-PDE)Pde5a Pde5Mus musculus (Mouse)Female gamete generation2K31glyphosate
858Q9JI70MKKS_MOUSEMolecular chaperone MKKS (McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin) (Protein Bbs6 homolog)Mkks Bbs6Mus musculus (Mouse)Male gamete generationQ9JI70glyphosate
859Q15645PCH2_HUMANPachytene checkpoint protein 2 homolog (Human papillomavirus type 16 E1 protein-binding protein) (16E1-BP) (HPV16 E1 protein-binding protein) (Thyroid hormone receptor interactor 13) (Thyroid receptor-interacting protein 13) (TR-interacting protein 13) (TRIP-13)TRIP13 PCH2Homo sapiens (Human)Female gamete generationQ15645glyphosate
860P03950ANGI_HUMANAngiogenin (EC 3.1.27.-) (Ribonuclease 5) (RNase 5)ANG RNASE5Homo sapiens (Human)Female gamete generationP03950glyphosate
861P16627HS71L_MOUSEHeat shock 70 kDa protein 1-like (Heat shock 70 kDa protein 1L) (Heat shock 70 kDa-like protein 1) (Spermatid-specific heat shock protein 70)Hspa1l Hsc70tMus musculus (Mouse)Male gamete generationP16627glyphosate
862Q61880DMC1_MOUSEMeiotic recombination protein DMC1/LIM15 homologDmc1 Dmc1h Lim15Mus musculus (Mouse)Female gamete generationQ61880glyphosate
863Q14623IHH_HUMANIndian hedgehog protein (IHH) (EC 3.1.-.-) (HHG-2) [Cleaved into: Indian hedgehog protein N-product]IHHHomo sapiens (Human)Female gamete generation3K7Iglyphosate
864O14686KMT2D_HUMANHistone-lysine N-methyltransferase 2D (Lysine N-methyltransferase 2D) (EC 2.1.1.364) (ALL1-related protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 2)KMT2D ALR MLL2 MLL4Homo sapiens (Human)Female gamete generation4Z4Pglyphosate
865P84244H33_MOUSEHistone H3.3H3-3a H3.3a H3f3a; H3-3b H3.3b H3f3bMus musculus (Mouse)Female gamete generation; Male gamete generation; Fertilization5XM1glyphosate
866P40692MLH1_HUMANDNA mismatch repair protein Mlh1 (MutL protein homolog 1)MLH1 COCA2Homo sapiens (Human)Female gamete generationP40692glyphosate
867P47791GSHR_MOUSEGlutathione reductase, mitochondrial (GR) (GRase) (EC 1.8.1.7)Gsr Gr1Mus musculus (Mouse)Male gamete generationP47791glyphosate
868P08228SODC_MOUSESuperoxide dismutase [Cu-Zn] (EC 1.15.1.1)Sod1Mus musculus (Mouse)Male gamete generation3GTVglyphosate
869P05480SRC_MOUSEProto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)SrcMus musculus (Mouse)Female gamete generation6F3Fglyphosate
870P10761ZP3_MOUSEZona pellucida sperm-binding protein 3 (Sperm receptor) (Zona pellucida glycoprotein 3) (Zp-3) (Zona pellucida protein C) [Cleaved into: Processed zona pellucida sperm-binding protein 3]Zp3 Zp-3 ZpcMus musculus (Mouse)Female gamete generation; Fertilization5OSQglyphosate

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For any questions on the database, please send E-mail to caoyuedi@sjtu.edu.cn.

Copyright © Haifeng Chen Lab, Shanghai Jiao Tong University.