Proteins with Transgenerational Effects on Disease or Function

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entries
No. Entry Entry Name Protein Names Gene Names Organism GO Biological Process Structure PDB ID for Docking Interaction Molecules
4276O88508DNM3A_MOUSEDNA (cytosine-5)-methyltransferase 3A (Dnmt3a) (EC 2.1.1.37) (Cysteine methyltransferase DNMT3A) (EC 2.1.1.-) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA) (M.MmuIIIA)Dnmt3aMus musculus (Mouse)Male gamete generation3SWCGenistein
4277Q91ZW2OFUT1_MOUSEGDP-fucose protein O-fucosyltransferase 1 (EC 2.4.1.221) (Peptide-O-fucosyltransferase 1) (O-FucT-1)Pofut1Mus musculus (Mouse)Embryo development5KXHGenistein
4278O00238BMR1B_HUMANBone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (CD antigen CDw293)BMPR1BHomo sapiens (Human)Female gamete generation3MDYGenistein
4279P05132KAPCA_MOUSEcAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)Prkaca PkacaMus musculus (Mouse)Male gamete generation; Embryo development7V0GGenistein
4280P40692MLH1_HUMANDNA mismatch repair protein Mlh1 (MutL protein homolog 1)MLH1 COCA2Homo sapiens (Human)Female gamete generationP40692Genistein
4281Q8CG03PDE5A_MOUSEcGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35) (cGMP-binding cGMP-specific phosphodiesterase) (CGB-PDE)Pde5a Pde5Mus musculus (Mouse)Female gamete generation2K31Genistein
4282Q01705NOTC1_MOUSENeurogenic locus notch homolog protein 1 (Notch 1) (Motch A) (mT14) (p300) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)]Notch1 MotchMus musculus (Mouse)Male gamete generation, Embryo development5KY4Genistein
4283P05532KIT_MOUSEMast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (CD antigen CD117)Kit SlMus musculus (Mouse)Male gamete generation2O26Genistein
4284Q80ZE5PAQR8_MOUSEMembrane progestin receptor beta (mPR beta) (Lysosomal membrane protein in brain 1) (Membrane progesterone P4 receptor beta) (Membrane progesterone receptor beta) (Progesterone and adipoQ receptor family member 8) (Progestin and adipoQ receptor family member 8) (Progestin and adipoQ receptor family member VIII)Paqr8 MprbMus musculus (Mouse)Female gamete generationQ80ZE5Genistein
4285P84244H33_MOUSEHistone H3.3H3-3a H3.3a H3f3a; H3-3b H3.3b H3f3bMus musculus (Mouse)Female gamete generation; Male gamete generation; Fertilization5XM1Genistein
4286Q8BYB9PGLT1_MOUSEProtein O-glucosyltransferase 1 (EC 2.4.1.376) (CAP10-like 46 kDa protein) (KTEL motif-containing protein 1) (O-glucosyltransferase Rumi homolog) (Rumi) (Protein O-xylosyltransferase POGLUT1) (EC 2.4.2.63) (Wing-shaped neural plate protein) (Wsnp)Poglut1 Clp46 Ktelc1Mus musculus (Mouse)embryo developmentQ8BYB9Genistein
4287Q80ZE4PAQR7_MOUSEMembrane progestin receptor alpha (mPR alpha) (Membrane progesterone P4 receptor alpha) (Membrane progesterone receptor alpha) (PPAR-gamma-induced liver protein) (Progesterone and adipoQ receptor family member 7) (Progestin and adipoQ receptor family member 7) (Progestin and adipoQ receptor family member VII)Paqr7 Mpra PglpMus musculus (Mouse)Female gamete generationQ80ZE4Genistein
4288Q9JK91MLH1_MOUSEDNA mismatch repair protein Mlh1 (MutL protein homolog 1)Mlh1Mus musculus (Mouse)Female gamete generationQ9JK91Genistein
4289Q021525HT2B_MOUSE5-hydroxytryptamine receptor 2B (5-HT-2B) (5-HT2B) (5-HT-2F) (NP75 protein) (Serotonin receptor 2B)Htr2bMus musculus (Mouse)embryo developmentQ02152Genistein
4290Q91VC3IF4A3_MOUSEEukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) (ATP-dependent RNA helicase DDX48) (ATP-dependent RNA helicase eIF4A-3) (DEAD box protein 48) (Eukaryotic translation initiation factor 4A isoform 3) [Cleaved into: Eukaryotic initiation factor 4A-III, N-terminally processed]Eif4a3 Ddx48Mus musculus (Mouse)embryo developmentQ91VC3Genistein

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Copyright © Haifeng Chen Lab, Shanghai Jiao Tong University.