Proteins with Transgenerational Effects on Disease or Function

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No. Entry Entry Name Protein Names Gene Names Organism GO Biological Process Structure PDB ID for Docking Interaction Molecules
3271Q96EB6SIR1_HUMANNAD-dependent protein deacetylase sirtuin-1 (hSIRT1) (EC 2.3.1.286) (NAD-dependent protein deacylase sirtuin-1) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 1) (SIR2-like protein 1) (hSIR2) [Cleaved into: SirtT1 75 kDa fragment (75SirT1)]SIRT1 SIR2L1Homo sapiens (Human)Male gamete generation4KXQMono(2-ethyl-5-oxohexyl)phthalate
3272Q14432PDE3A_HUMANcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A) (cGMP-inhibited cAMP phosphodiesterase) (cGI-PDE)PDE3AHomo sapiens (Human)Female gamete generation7L27Mono(2-ethyl-5-oxohexyl)phthalate
3273P41586PACR_HUMANPituitary adenylate cyclase-activating polypeptide type I receptor (PACAP type I receptor) (PACAP-R-1) (PACAP-R1)ADCYAP1R1Homo sapiens (Human)Male gamete generation3N94Mono(2-ethyl-5-oxohexyl)phthalate
3274P40692MLH1_HUMANDNA mismatch repair protein Mlh1 (MutL protein homolog 1)MLH1 COCA2Homo sapiens (Human)Female gamete generationP40692Mono(2-ethyl-5-oxohexyl)phthalate
3275Q9UQB9AURKC_HUMANAurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) (ARK-3) (Aurora-related kinase 3) (Aurora/IPL1/Eg2 protein 2) (Serine/threonine-protein kinase 13) (Serine/threonine-protein kinase aurora-C)AURKC AIE2 AIK3 AIRK3 ARK3 STK13Homo sapiens (Human)Female gamete generation6GR8Mono(2-ethyl-5-oxohexyl)phthalate
3276Q14094CCNI_HUMANCyclin-ICCNIHomo sapiens (Human)Male gamete generationQ14094Mono(2-ethyl-5-oxohexyl)phthalate
3277P08910ABHD2_HUMANMonoacylglycerol lipase ABHD2 (EC 3.1.1.23) (2-arachidonoylglycerol hydrolase) (Abhydrolase domain-containing protein 2) (Acetylesterase) (EC 3.1.1.6) (Lung alpha/beta hydrolase 2) (Progesterone-sensitive lipase) (EC 3.1.1.79) (Protein PHPS1-2)ABHD2 LABH2Homo sapiens (Human)Male gamete generationP08910Mono(2-ethyl-5-oxohexyl)phthalate
3278O00238BMR1B_HUMANBone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (CD antigen CDw293)BMPR1BHomo sapiens (Human)Female gamete generationO00238Mono(2-ethyl-5-oxohexyl)phthalate
3279O00238BMR1B_HUMANBone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (CD antigen CDw293)BMPR1BHomo sapiens (Human)Female gamete generation3MDYMono(2-ethyl-5-oxohexyl)phthalate
3280Q96MU7YTDC1_HUMANYTH domain-containing protein 1 (Splicing factor YT521) (YT521-B)YTHDC1 KIAA1966 YT521Homo sapiens (Human)Female gamete generation; Male gamete generation; embryo development6SZXMono(2-ethyl-5-oxohexyl)phthalate
3281Q5TAX3TUT4_HUMANTerminal uridylyltransferase 4 (TUTase 4) (EC 2.7.7.52) (Zinc finger CCHC domain-containing protein 11)TUT4 KIAA0191 ZCCHC11Homo sapiens (Human)Female gamete generation6IW6Mono(2-ethyl-5-oxohexyl)phthalate
3282Q14289FAK2_HUMANProtein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Related adhesion focal tyrosine kinase) (RAFTK)PTK2B FAK2 PYK2 RAFTKHomo sapiens (Human)Female gamete generation3FZSMono(2-ethyl-5-oxohexyl)phthalate
3283O00238BMR1B_HUMANBone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (CD antigen CDw293)BMPR1BHomo sapiens (Human)Female gamete generationO00238Mono(2-ethyl-5-oxohexyl)phthalate
3284Q8TC94ACTL9_HUMANActin-like protein 9ACTL9 ACTL7C HSD21Homo sapiens (Human)Male gamete generationQ8TC94Mono(2-ethyl-5-oxohexyl)phthalate
3285Q86VD1MORC1_HUMANMORC family CW-type zinc finger protein 1 (Cancer/testis antigen 33) (CT33)MORC1 MORCHomo sapiens (Human)Male gamete generationQ86VD1Mono(2-ethyl-5-oxohexyl)phthalate

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Copyright © Haifeng Chen Lab, Shanghai Jiao Tong University.