Proteins with Transgenerational Effects on Disease or Function

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No. Entry Entry Name Protein Names Gene Names Organism GO Biological Process Structure PDB ID for Docking Interaction Molecules
2251P16627HS71L_MOUSEHeat shock 70 kDa protein 1-like (Heat shock 70 kDa protein 1L) (Heat shock 70 kDa-like protein 1) (Spermatid-specific heat shock protein 70)Hspa1l Hsc70tMus musculus (Mouse)Male gamete generationP16627perfluorodecanoic acid
2252Q8NER5ACV1C_HUMANActivin receptor type-1C (EC 2.7.11.30) (Activin receptor type IC) (ACTR-IC) (Activin receptor-like kinase 7) (ALK-7)ACVR1C ALK7Homo sapiens (Human)Embryo developmentQ8NER5perfluorodecanoic acid
2253P37059DHB2_HUMAN17-beta-hydroxysteroid dehydrogenase type 2 (17-beta-HSD 2) (20 alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (E2DH) (Estradiol 17-beta-dehydrogenase 2) (EC 1.1.1.62) (Microsomal 17-beta-hydroxysteroid dehydrogenase) (Short chain dehydrogenase/reductase family 9C member 2) (Testosterone 17-beta-dehydrogenase) (EC 1.1.1.239)HSD17B2 EDH17B2 SDR9C2Homo sapiens (Human)Embryo developmentP37059perfluorodecanoic acid
2254P10275ANDR_HUMANAndrogen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)AR DHTR NR3C4Homo sapiens (Human)Fertilization; embryo development3V49perfluorodecanoic acid
2255A6ND01JUNO_HUMANSperm-egg fusion protein Juno (Folate receptor 4) (Folate receptor delta) (FR-delta) (IZUMO1 receptor protein JUNO)IZUMO1R FOLR4 JUNOHomo sapiens (Human)Fertilization5F4Qperfluorodecanoic acid
2256Q80ZE5PAQR8_MOUSEMembrane progestin receptor beta (mPR beta) (Lysosomal membrane protein in brain 1) (Membrane progesterone P4 receptor beta) (Membrane progesterone receptor beta) (Progesterone and adipoQ receptor family member 8) (Progestin and adipoQ receptor family member 8) (Progestin and adipoQ receptor family member VIII)Paqr8 MprbMus musculus (Mouse)Female gamete generationQ80ZE5Methylmercaptopurine riboside
2257Q8CG03PDE5A_MOUSEcGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35) (cGMP-binding cGMP-specific phosphodiesterase) (CGB-PDE)Pde5a Pde5Mus musculus (Mouse)Female gamete generation2K31Methylmercaptopurine riboside
2258Q8CDG1PIWL2_MOUSEPiwi-like protein 2 (EC 3.1.26.-)Piwil2 MiliMus musculus (Mouse)Female gamete generation; Male gamete generation4B9WMethylmercaptopurine riboside
2259P84244H33_MOUSEHistone H3.3H3-3a H3.3a H3f3a; H3-3b H3.3b H3f3bMus musculus (Mouse)Female gamete generation; Male gamete generation; Fertilization5XM1Methylmercaptopurine riboside
2260Q9JK91MLH1_MOUSEDNA mismatch repair protein Mlh1 (MutL protein homolog 1)Mlh1Mus musculus (Mouse)Female gamete generationQ9JK91Methylmercaptopurine riboside
2261Q99J09MEP50_MOUSEMethylosome protein 50 (MEP-50) (WD repeat-containing protein 77)Wdr77 Mep50Mus musculus (Mouse)Female gamete generationQ99J09Methylmercaptopurine riboside
2262P10761ZP3_MOUSEZona pellucida sperm-binding protein 3 (Sperm receptor) (Zona pellucida glycoprotein 3) (Zp-3) (Zona pellucida protein C) [Cleaved into: Processed zona pellucida sperm-binding protein 3]Zp3 Zp-3 ZpcMus musculus (Mouse)Female gamete generation; Fertilization5OSQMethylmercaptopurine riboside
2263Q61880DMC1_MOUSEMeiotic recombination protein DMC1/LIM15 homologDmc1 Dmc1h Lim15Mus musculus (Mouse)Female gamete generationQ61880Methylmercaptopurine riboside
2264P05480SRC_MOUSEProto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)SrcMus musculus (Mouse)Female gamete generation6F3FMethylmercaptopurine riboside
2265Q8C3P7MTA70_MOUSEN6-adenosine-methyltransferase subunit METTL3 (EC 2.1.1.348) (Methyltransferase-like protein 3) (N6-adenosine-methyltransferase 70 kDa subunit) (MT-A70)Mettl3 Mta70Mus musculus (Mouse)Female gamete generationQ8C3P7Methylmercaptopurine riboside

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Copyright © Haifeng Chen Lab, Shanghai Jiao Tong University.